In brief Post-ovulatory ageing of oocytes leads to poor oocyte and embryo quality as well as
abnormalities in offspring. This review provides an update on the contributions of oxidative …

Follicular microenvironment is paramount in the acquisition of oocyte competence, which is
dependent on two interconnected and interdependent processes: nuclear and cytoplasmic …

The quality of oocytes determines their development competence, which will be rapidly lost if
the oocytes are not fertilized at the proper time after ovulation. SIRT1, one of the sirtuin …

The quality of oocytes determines the development potential of an embryo and is dependent
on their timely fertilization after ovulation. Postovulatory oocyte aging is an inevitable factor …

Context Low ovarian putrescine levels and decreased peak values following luteinising
hormone peaks are related to poor oocyte quantity and quality in ageing women. Aims To …

The beneficial effect of glutathione (GSH) on the in vitro maturation (IVM) of bovine/porcine
oocytes has been confirmed; however, the antioxidant effect of exogenous GSH …

Germ cell quality is a key prerequisite for successful fertilization and early embryo
development. The quality is determined by the fine regulation of transcriptomic and …

Post-ovulatory aging, a major problem faced by oocytes cultured in vitro, causes oxidative
damage and mitochondrial dysfunction in oocytes. The ginsenoside Rh2 is one of the main …

Background The number of patients with type 1 diabetes rises rapidly around the world in
recent years. Maternal diabetes has a detrimental effect on reproductive outcomes due to …

线粒体自噬(mitophagy) 是一个进化保守的过程, 它可以选择性地识别, 隔离和降解特定靶标.
当细胞处于不利的环境下, 线粒体自噬通过降解异常或过量的线粒体来维持细胞稳态 …