Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning

G Heusch - Circulation research, 2015 - Am Heart Assoc
Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

Critical issues for the translation of cardioprotection

G Heusch - Circulation research, 2017 - Am Heart Assoc
The translation from numerous successful animal experiments on cardioprotection beyond
that by reperfusion to clinical practice has to date been disappointing. Animal experiments …

Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction

I Eitel, S De Waha, J Wöhrle, G Fuernau, P Lurz… - Journal of the American …, 2014 - jacc.org
Background: Although the prognostic value of findings from cardiac magnetic resonance
(CMR) imaging has been established in single-center center studies in patients with ST …

Cardiovascular magnetic resonance in acute st-segment–elevation myocardial infarction: Recent advances, controversies, and future directions

H Bulluck, R Dharmakumar, AE Arai, C Berry… - Circulation, 2018 - Am Heart Assoc
Although mortality after ST-segment elevation myocardial infarction (MI) is on the decline,
the number of patients developing heart failure as a result of MI is on the rise. Apart from …

Cardioprotection by remote ischemic conditioning and its signal transduction

P Kleinbongard, A Skyschally, G Heusch - Pflügers Archiv-European …, 2017 - Springer
Cardioprotective strategies aim to salvage myocardium from ischemia/reperfusion injury and
to reduce infarct size and its consequences. Different stimuli, acting at sites remote from the …

Time to give up on cardioprotection? A critical appraisal of clinical studies on ischemic pre-, post-, and remote conditioning

G Heusch, T Rassaf - Circulation research, 2016 - Am Heart Assoc
The mortality from acute myocardial infarction (AMI) remains significant, and the prevalence
of post-myocardial infarction heart failure is increasing. Therefore, cardioprotection beyond …

Effect of ischemic postconditioning during primary percutaneous coronary intervention for patients with ST-segment elevation myocardial infarction: a randomized …

T Engstrøm, H Kelbæk, S Helqvist, DE Høfsten… - JAMA …, 2017 - jamanetwork.com
Importance Ischemic postconditioning of the heart during primary percutaneous coronary
intervention (PCI) induced by repetitive interruptions of blood flow to the ischemic …

[HTML][HTML] Exosomes and cardioprotection–a critical analysis

SM Davidson, DM Yellon - Molecular aspects of medicine, 2018 - Elsevier
Exosomes are nano-sized vesicles released by numerous cell types that appear to have
diverse beneficial effects on the injured heart. Studies using exosomes from stem cells or …

Cardiac magnetic resonance imaging findings and the risk of cardiovascular events in patients with recent myocardial infarction or suspected or known coronary artery …

H El Aidi, A Adams, KGM Moons… - Journal of the American …, 2014 - jacc.org
The goal of this study was to review the prognostic value of cardiac magnetic resonance
(CMR) imaging findings for future cardiovascular events in patients with a recent myocardial …

Long-term prognostic value of cardiac MRI left atrial strain in ST-segment elevation myocardial infarction

S Leng, H Ge, J He, L Kong, Y Yang, F Yan, J Xiu… - Radiology, 2020 - pubs.rsna.org
Background Left atrial (LA) dysfunction is associated with morbidity and mortality. To the
knowledge of the authors, the relationship of LA strain to long-term prognosis in participants …