Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies
Genome-wide association studies (GWAS) provide biological insights into disease onset
and progression and have potential to produce clinically useful biomarkers. A growing body …
and progression and have potential to produce clinically useful biomarkers. A growing body …
Genetic architecture of subcortical brain structures in 38,851 individuals
Subcortical brain structures are integral to motion, consciousness, emotions and learning.
We identified common genetic variation related to the volumes of the nucleus accumbens …
We identified common genetic variation related to the volumes of the nucleus accumbens …
[HTML][HTML] Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the enhancing neuro imaging genetics through meta …
Background The profile of cortical neuroanatomical abnormalities in schizophrenia is not
fully understood, despite hundreds of published structural brain imaging studies. This study …
fully understood, despite hundreds of published structural brain imaging studies. This study …
Brain circuitry of compulsivity
OA Van den Heuvel, G van Wingen… - European …, 2016 - Elsevier
Compulsivity is associated with alterations in the structure and the function of parallel and
interacting brain circuits involved in emotional processing (involving both the reward and the …
interacting brain circuits involved in emotional processing (involving both the reward and the …
ENIGMA MDD: seven years of global neuroimaging studies of major depression through worldwide data sharing
A key objective in the field of translational psychiatry over the past few decades has been to
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …
identify the brain correlates of major depressive disorder (MDD). Identifying measurable …
Functional connectomics in depression: insights into therapies
Depression is a common mental disorder characterized by heterogeneous cognitive and
behavioral symptoms. The emerging research paradigm of functional connectomics has …
behavioral symptoms. The emerging research paradigm of functional connectomics has …
[HTML][HTML] Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies
Individual differences in cognitive performance increase with advancing age, reflecting
marked cognitive changes in some individuals along with little or no change in others …
marked cognitive changes in some individuals along with little or no change in others …
JuSpace: A tool for spatial correlation analyses of magnetic resonance imaging data with nuclear imaging derived neurotransmitter maps
Recent studies have shown that druginduced spatial alteration patterns in resting state
functional activity as measured using magnetic resonance imaging (rsfMRI) are associated …
functional activity as measured using magnetic resonance imaging (rsfMRI) are associated …
Machine learning approaches for clinical psychology and psychiatry
Machine learning approaches for clinical psychology and psychiatry explicitly focus on
learning statistical functions from multidimensional data sets to make generalizable …
learning statistical functions from multidimensional data sets to make generalizable …
Prediction complements explanation in understanding the developing brain
A central aim of human neuroscience is understanding the neurobiology of cognition and
behavior. Although we have made significant progress towards this goal, reliance on group …
behavior. Although we have made significant progress towards this goal, reliance on group …