Clinical pharmacology of oral anticoagulants in patients with kidney disease

N Jain, RF Reilly - Clinical Journal of the American Society of …, 2019 - journals.lww.com
Oral anticoagulants are commonly used drugs in patients with CKD and patients with ESKD
to treat atrial fibrillation to reduce stroke and systemic embolism. Some of these drugs are …

A systematic review of direct oral anticoagulant use in chronic kidney disease and dialysis patients with atrial fibrillation

J Feldberg, P Patel, A Farrell… - Nephrology Dialysis …, 2019 - academic.oup.com
Background There is a lack of clear benefit and a potential risk of bleeding with direct oral
anticoagulant (DOAC) use in chronic kidney disease (CKD) and dialysis patients with atrial …

Chronic kidney disease and arrhythmias: conclusions from a kidney disease: improving global outcomes (KDIGO) controversies conference

MP Turakhia, PJ Blankestijn, JJ Carrero… - European heart …, 2018 - academic.oup.com
Patients with chronic kidney disease (CKD) are predisposed to heart rhythm disorders,
including atrial fibrillation (AF)/atrial flutter, supraventricular tachycardias, ventricular …

[HTML][HTML] Anticoagulation in patients with chronic kidney disease

EJ Elenjickal, CK Travlos, P Marques… - American Journal of …, 2024 - karger.com
Background: Both atrial fibrillation and venous thromboembolism (VTE) are highly prevalent
among patients with chronic kidney disease (CKD). Until recently, warfarin was the most …

Direct oral anticoagulant use in chronic kidney disease and dialysis patients with venous thromboembolism: a systematic review of thrombosis and bleeding outcomes

CYS Cheung, J Parikh, A Farrell… - Annals of …, 2021 - journals.sagepub.com
Objective: To evaluate how treatment with DOACs for VTE affects thrombosis and bleeding
outcomes compared to warfarin in CKD and dialysis patients. Data Sources: A literature …

The use of direct oral anticoagulants in chronic kidney disease

K Parker, J Thachil - British journal of haematology, 2018 - Wiley Online Library
Increasing use of direct oral anticoagulants (DOAC s) has made management of non‐
valvular atrial fibrillation and venous thromboembolism easier in most patients. But the …

Prescription of DOACs in patients with atrial fibrillation at different stages of renal insufficiency

K Hahn, M Lamparter - Advances in Therapy, 2023 - Springer
Atrial fibrillation (AF) and renal insufficiency often coexist and are increasingly prevalent with
advancing age. Both the risk of thromboembolic events and bleeding propensity are higher …

Novel oral anticoagulants in patients with chronic kidney disease and atrial fibrillation

E Stamellou, J Floege - Nephrology Dialysis Transplantation, 2018 - academic.oup.com
Atrial fibrillation (AF) is the most frequent arrhythmia in common clinical practice and its
prevalence is markedly increased among patients with chronic kidney disease (CKD). The …

Direct oral anticoagulants in patients with atrial fibrillation and renal impairment, extremes in weight, or advanced age

LF Buckley, E Rybak, A Aldemerdash… - Clinical …, 2017 - Wiley Online Library
A growing number of patients with an indication for stroke prevention in atrial fibrillation have
kidney‐, age‐, or weight‐related alterations in pharmacokinetics that affect dosing of direct …

[HTML][HTML] Influence of renal function on the pharmacokinetics, pharmacodynamics, efficacy, and safety of non–vitamin K antagonist oral anticoagulants

MR Weir, R Kreutz - Mayo Clinic Proceedings, 2018 - Elsevier
With the growing integration of non–vitamin K antagonist oral anticoagulants (NOACs) into
clinical practice, questions have arisen regarding their use in special populations, including …