The existence of males and females is due to two processes: sex determi nation and
differentiation. Sex determination is the process of choosing either the male or the female …

Sry is the Y-chromosomal gene that acts as a trigger for male development in mammalian
embryos. This gene encodes a high mobility group (HMG) box transcription factor that is …

In humans, activation of genes in the testis-determining pathway at 7–8 weeks gestation
causes the bipotential gonad to develop as a testis. The first morphologically recognisable …

Haqq, Christopher M., and Patricia K. Donahoe. Regulation of Sexual Dimorphism in
Mammals. Physiol. Rev. 78: 1–33, 1998.—Sexual dimorphism in humans has been the …

The Y chromosome located gene SRY (sex determining region Y gene) was identified in the
search for the mammalian testis determining factor (TDF). Approaches for evaluating SRY as …

In mammals, sex is determined by the Y chromosome, which encodes a testis-determining
factor (TDF). This factor causes the undifferentiated embryonic gonads to develop as testes …

The decision of the bi-potential gonad to develop into either a testis or ovary is determined
by the presence or absence of the Sex-determining Region gene on the Y chromosome …

The SRY gene (sex-determining region of the Y chromosome) initiates the process of male
sex differentiation in mammalians. In humans mutations in the SRY gene have been …

In humans, the choice between male or female development is genetically determined. Sex
determination occurs as the undifferentiated and bipotential embryonic gonad becomes …

XY gonadal dysgenesis can be classified as either complete or incomplete according to
gonadal morphology. The disease is a sex-reversal disorder resulting from embryonic …