Gut microbiome lipid metabolism and its impact on host physiology

EM Brown, J Clardy, RJ Xavier - Cell Host & Microbe, 2023 - cell.com
Metabolites produced by commensal gut microbes impact host health through their
recognition by the immune system and their influence on numerous metabolic pathways …

Inflammation and malnutrition in inflammatory bowel disease

S Massironi, C Viganò, A Palermo, L Pirola… - The Lancet …, 2023 - thelancet.com
Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis,
has become increasingly prevalent worldwide in the past decade. The nutritional status of …

Implications of the changing epidemiology of inflammatory bowel disease in a changing world

M Agrawal, T Jess - United European Gastroenterology Journal, 2022 - Wiley Online Library
The epidemiology of inflammatory bowel disease (IBD) has undergone considerable shifts
since its emergence in the Western world over a century ago, especially in the last few …

Diet fuelling inflammatory bowel diseases: Preclinical and clinical concepts

TE Adolph, J Zhang - Gut, 2022 - gut.bmj.com
The diet and gut microbiota have been extensively interrogated as a fuel for gut
inflammation in inflammatory bowel diseases (IBDs) in the last few years. Here, we review …

Engineering fucoxanthin-loaded probiotics' membrane vesicles for the dietary intervention of colitis

D Liang, C Liu, Y Li, C Wu, Y Chen, M Tan, W Su - Biomaterials, 2023 - Elsevier
Extracellular vesicles (EVs) are very attractive as carriers of active components due to their
good immunological and their ability to penetrate the physiological barrier that synthetic …

[HTML][HTML] The epidemiology of inflammatory bowel disease: Clues to pathogenesis?

SM Borowitz - Frontiers in Pediatrics, 2023 - frontiersin.org
Historically, inflammatory bowel disease (IBD) was most common in North America and
Europe and more common with a north-south gradient. Over the past century, there has …

Multifunctional two-dimensional Bi2Se3 nanodiscs for anti-inflammatory therapy of inflammatory bowel diseases

C Zhang, Q Li, J Shan, J Xing, X Liu, Y Ma, H Qian… - Acta Biomaterialia, 2023 - Elsevier
The overexpression of reactive oxygen and nitrogen species (RONS) in the colonic mucosa
destroys the mucosa and its barrier, accelerating the occurrence of inflammatory bowel …

Impact of female gender in inflammatory bowel diseases: a narrative review

L Lungaro, A Costanzini, F Manza… - Journal of Personalized …, 2023 - mdpi.com
Inflammatory bowel diseases show a gender bias, as reported for several other immune-
mediated diseases. Female-specific differences influence disease presentation and activity …

Microbiota metabolism of intestinal amino acids impacts host nutrient homeostasis and physiology

TT Li, X Chen, D Huo, M Arifuzzaman, S Qiao, WB Jin… - Cell Host & Microbe, 2024 - cell.com
The intestine and liver are thought to metabolize dietary nutrients and regulate host nutrient
homeostasis. Here, we find that the gut microbiota also reshapes the host amino acid (aa) …

Genetic and dietary modulators of the inflammatory response in the gastrointestinal tract of the BXD mouse genetic reference population

X Li, JD Morel, G Benegiamo, J Poisson, A Bachmann… - Elife, 2023 - elifesciences.org
Inflammatory gut disorders, including inflammatory bowel disease (IBD), can be impacted by
dietary, environmental, and genetic factors. While the incidence of IBD is increasing …