Piezo1 channel activation facilitates baroreflex afferent neurotransmission with subsequent blood pressure reduction in control and hypertension rats
Mechanosensitive cation channels such as Piezo1 and Piezo2 are activated by mechanical
force like a starched wall of the aorta while blood pressure (BP) rising, which helps to …
force like a starched wall of the aorta while blood pressure (BP) rising, which helps to …
The baroreflex afferent pathway plays a critical role in H2S-mediated autonomic control of blood pressure regulation under physiological and hypertensive conditions
Y Li, Y Feng, L Liu, X Li, X Li, X Sun, K Li… - Acta Pharmacologica …, 2021 - nature.com
Abstract Hydrogen sulfide (H2S), which is closely related to various cardiovascular
disorders, lowers blood pressure (BP), but whether this action is mediated via the …
disorders, lowers blood pressure (BP), but whether this action is mediated via the …
A second wave for the neurokinin Tac2 pathway in brain research
Despite promising advances in basic research of the neurokinin B/Tac2 pathway in both
animals and humans, clinical applications are yet to be implemented. This is likely because …
animals and humans, clinical applications are yet to be implemented. This is likely because …
FGF-21 ameliorates essential hypertension of SHR via baroreflex afferent function
P Chen, B Xu, Y Feng, KX Li, Z Liu, X Sun, XL Lu… - Brain Research …, 2020 - Elsevier
Hypertension is a common complication of metabolic abnormalities associated with
cardiovascular system and characterized by sexual dimorphism in mammals. Fibroblast …
cardiovascular system and characterized by sexual dimorphism in mammals. Fibroblast …
Mechanical tibial loading remotely suppresses brain tumors by dopamine-mediated downregulation of CCN4
Y Fan, R Zha, T Sano, X Zhao, S Liu, MD Woollam… - Bone Research, 2021 - nature.com
Mechanical loading to the bone is known to be beneficial for bone homeostasis and for
suppressing tumor-induced osteolysis in the loaded bone. However, whether loading to a …
suppressing tumor-induced osteolysis in the loaded bone. However, whether loading to a …
Intrathecally administered substance P activated the spinal defecation center and enhanced colorectal motility in anesthetized rats
K Naitou, H Iwashita, HH Ueda… - American Journal …, 2022 - journals.physiology.org
Noxious stimuli on the colorectum cause colorectal contractions through activation of
descending monoaminergic pathways projecting from the supraspinal defecation center to …
descending monoaminergic pathways projecting from the supraspinal defecation center to …
Estrogen-dependent KCa1. 1 modulation is essential for retaining neuroexcitation of female-specific subpopulation of myelinated Ah-type baroreceptor neurons in rats
L Wang, Z Qian, H Ma, M Zhou, H Li, C Cui… - Acta Pharmacologica …, 2021 - nature.com
Female-specific subpopulation of myelinated Ah-type baroreceptor neurons (BRNs) in
nodose ganglia is the neuroanatomical base of sexual-dimorphic autonomic control of blood …
nodose ganglia is the neuroanatomical base of sexual-dimorphic autonomic control of blood …
Bradykinin‐mediated estrogen‐dependent depressor response by direct activation of female‐specific distribution of myelinated Ah‐type baroreceptor neurons in rats
KX Li, Y Feng, XX Fan, X Sun, Y Li… - CNS Neuroscience …, 2022 - Wiley Online Library
Aim To understand the direct impact of bradykinin in autonomic control of circulation through
baroreflex afferent pathway. Methods The mean arterial pressure (MAP) was monitored …
baroreflex afferent pathway. Methods The mean arterial pressure (MAP) was monitored …