[HTML][HTML] RNA modifications: importance in immune cell biology and related diseases
L Cui, R Ma, J Cai, C Guo, Z Chen, L Yao… - Signal transduction and …, 2022 - nature.com
RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …
including generation, transportation, function, and metabolization, they act as critical …
Mitochondrial complex II: at the crossroads
Mitochondrial complex II (CII), also called succinate dehydrogenase (SDH), is a central
purveyor of the reprogramming of metabolic and respiratory adaptation in response to …
purveyor of the reprogramming of metabolic and respiratory adaptation in response to …
[HTML][HTML] Cannabidiol as a potential treatment for anxiety and mood disorders: molecular targets and epigenetic insights from preclinical research
Cannabidiol (CBD) is the most abundant non-psychoactive component of cannabis; it
displays a very low affinity for cannabinoid receptors, facilitates endocannabinoid signaling …
displays a very low affinity for cannabinoid receptors, facilitates endocannabinoid signaling …
Transgenerational epigenetic inheritance in mammals: how good is the evidence?
SD van Otterdijk, KB Michels - The FASEB Journal, 2016 - Wiley Online Library
Epigenetics plays an important role in orchestrating key biologic processes. Epigenetic
marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are …
marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are …
[HTML][HTML] Epigenetic inheritance and its role in evolutionary biology: re-evaluation and new perspectives
W Burggren - Biology, 2016 - mdpi.com
Epigenetics increasingly occupies a pivotal position in our understanding of inheritance,
natural selection and, perhaps, even evolution. A survey of the PubMed database, however …
natural selection and, perhaps, even evolution. A survey of the PubMed database, however …
[HTML][HTML] Alpha-ketoglutarate as a molecule with pleiotropic activity: well-known and novel possibilities of therapeutic use
B Zdzisińska, A Żurek, M Kandefer-Szerszeń - Archivum immunologiae et …, 2017 - Springer
Abstract Alpha-ketoglutarate (AKG), an endogenous intermediary metabolite in the Krebs
cycle, is a molecule involved in multiple metabolic and cellular pathways. It functions as an …
cycle, is a molecule involved in multiple metabolic and cellular pathways. It functions as an …
Epigenetic alterations induced by genotoxic occupational and environmental human chemical carcinogens: A systematic literature review
Accumulating evidence suggests that epigenetic alterations play an important role in
chemically-induced carcinogenesis. Although the epigenome and genome may be equally …
chemically-induced carcinogenesis. Although the epigenome and genome may be equally …
[HTML][HTML] Epigenetics of pregnancy: looking beyond the DNA code
D Zuccarello, U Sorrentino, V Brasson, L Marin… - Journal of Assisted …, 2022 - Springer
Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …
gene expression without direct modification of the DNA sequence. An ever-increasing …
[HTML][HTML] Epigenetic activities of flavonoids in the prevention and treatment of cancer
C Busch, M Burkard, C Leischner, UM Lauer, J Frank… - Clinical …, 2015 - Springer
Aberrant epigenetic modifications are described in an increasing number of pathological
conditions, including neurodegenerative diseases, cardiovascular diseases, diabetes …
conditions, including neurodegenerative diseases, cardiovascular diseases, diabetes …
Genetic mechanisms of fertilization failure and early embryonic arrest: a comprehensive review
Y Wei, J Wang, R Qu, W Zhang, Y Tan… - Human …, 2024 - academic.oup.com
BACKGROUND Infertility and pregnancy loss are longstanding problems. Successful
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …
fertilization and high-quality embryos are prerequisites for an ongoing pregnancy. Studies …