Previous studies indicate that estrogen positively regulates lung cancer progression.
Understanding the reasons will be beneficial for treating women with lung cancer in the …

Background Renal cell carcinoma (RCC) is a common malignant tumor of the urinary
system. Angiogenesis is a main contributing factor for tumorigenesis. E74-like transcription …

Gastric cancer is a highly malignant tumor. Gastric cancer stem cells (GCSCs) are the main
causes of drug resistance, metastasis, recurrence, and poor prognosis. As a secondary …

During embryo development, DNA methylation is established by DNMT3A/3B and
subsequently maintained by DNMT1. While much research has been done in this field, the …

Background Cancer-associated fibroblasts (CAFs) are essential components of the tumor
microenvironment (TME). These cells play a supportive role throughout cancer progression …

In countries around the world, sleep deprivation represents a widespread problem affecting
school‐age children, teenagers, and adults. Acute sleep deprivation and more chronic sleep …

Tumor biomarkers, the substances which are produced by tumors or the body's responses to
tumors during tumorigenesis and progression, have been demonstrated to possess critical …

Glaucoma is the world's leading irreversible blinding eye disease. Lowering intraocular
pressure is currently the only effective clinical treatment. However, there is a lack of long …

ABSTRACT DNA methylation affects expression of associated genes and may contribute to
the missing genetic effects from genome-wide association studies of osteoporosis. To …

While it is well known that expression levels of metabolic enzymes regulate the metabolic
state of the cell, there is mounting evidence that the converse is also true, that metabolite …