DNA methylation is a crucial regulatory mechanism in many biological processes. However,
limited studies have dissected the contribution of DNA methylation to sexual differentiation in …

Hepatoblastoma is a malignant embryonal tumor with multiple differentiation modes and is
the clearest liver malignancy in children. However, little is known about genetic and …

Although hepatocellular carcinoma (HCC) is rather frequent, little is known about the
molecular pathways underlying its development, progression, and prognosis. In the current …

The leading causes of death across the world are cancer, cardiovascular diseases and
chronic lower respiratory diseases, cerebrovascular diseases, Alzheimer's disease, diabetes …

Skin aging is characterized by wrinkle formation and increased frailty and laxity, leading to
the risk of age-related skin diseases. Keratinocyte is an important component of the …

Colorectal cancer (CRC) is one of the most common cancer types globally with a 5‐year
survival rate of< 50% in China. Aberrant DNA methylation is one of the hallmarks of tumor …

DNA methylation is important in developing and post-mitotic cells in various tissues. Recent
studies have shown that DNA methylation is highly dynamic, and plays important roles …

Simple Summary The members of the TFF family have been illustrated to be tumor
suppressor genes in various malignancies. In this study, we first identified that TFF1/TFF2 …

Studies have shown that lead (Pb) exposure caused genotoxicity, however, the underlying
mechanisms remain unclear. A mechanism may be via DNA methylation which is one of the …

Osteoporosis (OP) is a metabolic disease that affects bone, resulting in a progressive
decrease in bone mass, quality, and micro-architectural degeneration. Natural products …