Potential strategies to control the risk of antifungal resistance in humans: A comprehensive review

AA Rabaan, T Sulaiman, SH Al-Ahmed, ZA Buhaliqah… - Antibiotics, 2023 - mdpi.com
Fungal infections are becoming one of the main causes of morbidity and mortality in people
with weakened immune systems. Mycoses are becoming more common, despite greater …

[引用][C] Therapeutic aspects of berberine and its derivatives: recent advances and challenges

S Karimi, F Heidari, S Amraei - Nano Micro Biosystems, 2023 - nmb-journal.com
There is an urgent need for the discovery of biocompatible therapeutic drugs that can be
administered for long periods without severe side effects. Berberine is an alkaloid …

Developing novel coumarin-containing azoles antifungal agents by the scaffold merging strategy for treating azole-resistant candidiasis

Z Yan, Y Huang, D Zhao, Z Li, X Wang… - Journal of Medicinal …, 2023 - ACS Publications
The extensive use of antifungal drugs has resulted in severe drug resistance, making clinical
treatment of fungal infections more difficult. Biofilm inhibitors can overcome drug resistance …

Nucleoside analogues: N-glycosylation methodologies, synthesis of antiviral and antitumor drugs and potential against drug-resistant bacteria and Alzheimer's …

C Maria, AP Rauter - Carbohydrate Research, 2023 - Elsevier
Nucleosides have gained significant attention since the discovery of the structure of DNA.
Nucleoside analogues may be synthesized through multiple synthetic pathways, however …

Antifungal activity of mycogenic silver nanoparticles on clinical yeasts and phytopathogens

LG Ribeiro, GSC Roque, R Conrado, AO De Souza - Antibiotics, 2023 - mdpi.com
In this study, seven different silver nanoparticles (AgNPs) were obtained using the fungi
species from the phylum Ascomycota, Aspergillus tubingensis, Aspergillus spp …

Diagnostic Efficacy of LAMP Assay for Human Fungal Pathogens: a Systematic Review and Meta-analysis

GS Bumbrah, S Jain, S Singh, Z Fatima… - Current Fungal Infection …, 2023 - Springer
Purpose Human fungal infections particularly caused by Candida and Aspergillus have
emerged as major public health burden. Long turnaround time and poor sensitivity of the …

Enhanced Solubility and Bioavailability of Clotrimazole in Aqueous Solutions with Hydrophobized Hyperbranched Polyglycidol for Improved Antifungal Activity

D Jaworska-Krych, M Gosecka, M Gosecki… - … Applied Materials & …, 2024 - ACS Publications
The poor solubility of clotrimazole in the aqueous medium and the uncontrolled removal of
the drug-loaded suppository content limit its effectiveness in the treatment of vulvovaginal …

Antifungals: From Pharmacokinetics to Clinical Practice

A Carmo, M Rocha, P Pereirinha, R Tomé, E Costa - Antibiotics, 2023 - mdpi.com
The use of antifungal drugs started in the 1950s with polyenes nystatin, natamycin and
amphotericin B-deoxycholate (AmB). Until the present day, AmB has been considered to be …

Anti-Malassezia Drug Candidates Based on Virulence Factors of Malassezia-Associated Diseases

M Billamboz, S Jawhara - Microorganisms, 2023 - mdpi.com
Malassezia is a lipophilic unicellular fungus that is able, under specific conditions, to cause
severe cutaneous and systemic diseases in predisposed subjects. This review is divided …

Computer-made peptide RQ18 acts as a dual antifungal and antibiofilm peptide though membrane-associated mechanisms of action

CV Almeida, CFR de Oliveira… - Archives of Biochemistry …, 2024 - Elsevier
The spread of fungi resistant to conventional drugs has become a threatening problem. In
this context, antimicrobial peptides (AMPs) have been considered as one of the main …