Epidemiology of invasive candidiasis: a persistent public health problem
MA Pfaller, DJ Diekema - Clinical microbiology reviews, 2007 - Am Soc Microbiol
Invasive candidiasis (IC) is a leading cause of mycosis-associated mortality in the United
States. We examined data from the National Center for Health Statistics and reviewed recent …
States. We examined data from the National Center for Health Statistics and reviewed recent …
Echinocandin antifungal drugs
DW Denning - The Lancet, 2003 - thelancet.com
The echinocandins are large lipopeptide molecules that are inhibitors of β-(1, 3)-glucan
synthesis, an action that damages fungal cell walls. In vitro and in vivo, the echinocandins …
synthesis, an action that damages fungal cell walls. In vitro and in vivo, the echinocandins …
Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the Infectious Diseases Society of America
TF Patterson, GR Thompson III… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …
patients. They are not intended to supplant physician judgment with respect to particular …
Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America
TJ Walsh, EJ Anaissie, DW Denning, R Herbrecht… - Clinical infectious …, 2008 - JSTOR
Aspergillus species have emerged as an important cause of life-threatening infections in
immunocompromised patients. This expanding population is composed of patients with …
immunocompromised patients. This expanding population is composed of patients with …
Invasive fungal infections: a review of epidemiology and management options
DA Enoch, HA Ludlam… - Journal of medical …, 2006 - microbiologyresearch.org
Fungi are increasingly recognised as major pathogens in critically ill patients. Candida spp.
and Cryptococcus spp. are the yeasts most frequently isolated in clinical practice. The most …
and Cryptococcus spp. are the yeasts most frequently isolated in clinical practice. The most …
Coccidioidomycosis
JN Galgiani, NM Ampel, JE Blair… - Clinical Infectious …, 2005 - academic.oup.com
Management of coccidioidomycosis first involves recognizing that a coccidioidal infection
exists, defining the extent of infection, and identifying host factors that predispose to disease …
exists, defining the extent of infection, and identifying host factors that predispose to disease …
Invasive fungal pathogens: current epidemiological trends
MA Pfaller, PG Pappas… - Clinical Infectious Diseases, 2006 - academic.oup.com
Patient characteristics, antifungal prophylaxis, and other factors appear to have contributed
to a change in the spectrum of invasive fungal pathogens. Infections with Candida glabrata …
to a change in the spectrum of invasive fungal pathogens. Infections with Candida glabrata …
Invasive aspergillosis: epidemiology, diagnosis and management in immunocompromised patients
G Maschmeyer, A Haas, OA Cornely - Drugs, 2007 - Springer
Morbidity and mortality caused by invasive Aspergillus infections are increasing. This is
because of the higher number of patients with malignancies treated with intensive …
because of the higher number of patients with malignancies treated with intensive …
Combination treatment of invasive fungal infections
PK Mukherjee, DJ Sheehan, CA Hitchcock… - Clinical microbiology …, 2005 - Am Soc Microbiol
The persistence of high morbidity and mortality from systemic fungal infections despite the
availability of novel antifungals points to the need for effective treatment strategies …
availability of novel antifungals points to the need for effective treatment strategies …
Micafungin (FK463), alone or in combination with other systemic antifungal agents, for the treatment of acute invasive aspergillosis
DW Denning, KA Marr, WM Lau, DP Facklam… - Journal of Infection, 2006 - Elsevier
BACKGROUND: Micafungin (FK463) is a new lipopeptide compound (echinocandin) with
activity against Aspergillus and Candida species. This study evaluated the safety and …
activity against Aspergillus and Candida species. This study evaluated the safety and …