Biliary Atresia is a devastating pediatric cholangiopathy affecting the bile ducts of the liver. In
this review, we describe recent progress in the understanding of liver development with a …

Cholestatic liver diseases including primary biliary cholangitis (PBC) and primary sclerosing
cholangitis (PSC) are associated with active hepatic fibrogenesis, which can ultimately lead …

Background Biliary atresia (BA) is the most common obstructive cholangiopathy in neonates,
often progressing to end-stage cirrhosis. BA pathogenesis is believed to be multifactorial …

Fibulin-3 (also known as EGF-containing fibulin extracellular matrix protein 1 (EFEMP1)) is a
secreted extracellular matrix glycoprotein, encoded by the EFEMP1 gene that belongs to the …

Background Biliary atresia (BA) is a devastating inflammatory and fibrosing cholangiopathy
of neonates with unknown aetiology. We aim to investigate the relationship between these …

Background & Aims Biliary atresia (BA) is poorly understood and leads to liver
transplantation (LT), with the requirement for and associated risks of lifelong …

Background and Aims Biliary atresia (BA) is a poorly understood and devastating obstructive
bile duct disease of newborns. It is often diagnosed late, is incurable and frequently requires …

Despite decades since its description and decades of intensive researches, cause of biliary
atresia disease remains enigmatic. The inheritance of biliary atresia is not Mendelian …

Biliary atresia (BA) is the most prevalent serious liver disease of infancy and childhood, and
the principal indication for liver transplantation in pediatrics. BA is best considered as an …

Background While there is strong evidence that genetic risk factors play an important role in
the etiologies of structural birth defects, compared to other diseases, there have been …