Brain injury is one of the most consequential problems facing neonates, with many preterm
and term infants at risk for cerebral hypoxia and ischemia. To develop effective …

Cerebral blood flow (CBF) is an important physiologic parameter that is vital for proper
cerebral function and recovery. Current widely accepted methods of measuring CBF are …

Diffuse correlation spectroscopy (DCS) has emerged as a versatile, noninvasive method for
deep tissue perfusion assessment using near-infrared light. A broad class of applications is …

Abstract Significance: Intracranial pressure (ICP), variability in perfusion, and resulting
ischemia are leading causes of secondary brain injury in patients treated in the …

Significance Bedside cerebral blood flow (CBF) monitoring has the potential to inform and
improve care for acute neurologic diseases, but technical challenges limit the use of existing …

A major concern with preterm birth is the risk of neurodevelopmental disability. Poor cerebral
circulation leading to periods of hypoxia is believed to play a significant role in the etiology …

Hyperventilation (HV) therapy uses vasoconstriction to reduce intracranial pressure (ICP) by
reducing cerebral blood volume. However, as HV also lowers cerebral blood flow (CBF), it …

Objectives Real-time noninvasive monitoring of cerebral blood flow (CBF) during surgery is
key to reducing mortality rates associated with adult cardiac surgeries requiring hypothermic …

Cerebrovascular reactivity defines the ability of the cerebral vasculature to regulate its
resistance in response to both local and systemic factors to ensure an adequate cerebral …

Dynamic cerebral autoregulation (dCA) can be derived from spontaneous oscillations in
arterial blood pressure (ABP) and cerebral blood flow (CBF). Transcranial Doppler (TCD) …