The microbiota-gut-brain axis
I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …
[HTML][HTML] The Interaction of Person-Affect-Cognition-Execution (I-PACE) model for addictive behaviors: Update, generalization to addictive behaviors beyond internet …
We propose an updated version of the Interaction of Person-Affect-Cognition-Execution (I-
PACE) model, which we argue to be valid for several types of addictive behaviors, such as …
PACE) model, which we argue to be valid for several types of addictive behaviors, such as …
Opioid use disorder
J Strang, ND Volkow, L Degenhardt… - Nature reviews Disease …, 2020 - nature.com
Opioid use disorder (OUD) is a chronic relapsing disorder that, whilst initially driven by
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …
activation of brain reward neurocircuits, increasingly engages anti-reward neurocircuits that …
Alcohol and the brain: neuronal molecular targets, synapses, and circuits
KP Abrahao, AG Salinas, DM Lovinger - Neuron, 2017 - cell.com
Ethanol is one of the most commonly abused drugs. Although environmental and genetic
factors contribute to the etiology of alcohol use disorders, it is ethanol's actions in the brain …
factors contribute to the etiology of alcohol use disorders, it is ethanol's actions in the brain …
Addiction and stress: An allostatic view
GF Koob, J Schulkin - Neuroscience & Biobehavioral Reviews, 2019 - Elsevier
Allostasis, or stability through change, has most often been linked with challenges to
homeostasis, in which repeated challenges or stressors produce sufficient allostatic load to …
homeostasis, in which repeated challenges or stressors produce sufficient allostatic load to …
[HTML][HTML] Stress-induced plasticity and functioning of ventral tegmental dopamine neurons
EH Douma, ER de Kloet - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
The ventral tegmental area dopamine (VTA-DA) mesolimbic circuit processes emotional,
motivational, and social reward associations together with their more demanding cognitive …
motivational, and social reward associations together with their more demanding cognitive …
Drug addiction: hyperkatifeia/negative reinforcement as a framework for medications development
GF Koob - Pharmacological Reviews, 2021 - ASPET
Compulsive drug seeking that is associated with addiction is hypothesized to follow a
heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect …
heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect …
Common brain mechanisms of chronic pain and addiction
I Elman, D Borsook - Neuron, 2016 - cell.com
While chronic pain is considered by some to be a CNS disease, little is understood about
underlying neurobiological mechanisms. Addiction models have heuristic value in this …
underlying neurobiological mechanisms. Addiction models have heuristic value in this …
Epigenetic mechanisms of opioid addiction
Opioid use kills tens of thousands of Americans each year, devastates families and entire
communities, and cripples the health care system. Exposure to opioids causes long-term …
communities, and cripples the health care system. Exposure to opioids causes long-term …
Opioid receptors: drivers to addiction?
E Darcq, BL Kieffer - Nature Reviews Neuroscience, 2018 - nature.com
Drug addiction is a worldwide societal problem and public health burden, and results from
recreational drug use that develops into a complex brain disorder. The opioid system, one of …
recreational drug use that develops into a complex brain disorder. The opioid system, one of …