Post-complexation functionalization of cyclometalated iridium (III) complexes and applications to biomedical and material sciences

S Aoki, K Yokoi, Y Hisamatsu, C Balachandran… - Metal Ligand …, 2022 - Springer
Abstract Cyclometalated iridium (III)(Ir (III)) complexes exhibit excellent photophysical
properties that include large Stokes shift, high emission quantum yields, and microsecond …

Multimodal probes: superresolution and transmission electron microscopy imaging of mitochondria, and oxygen mapping of cells, using small-molecule Ir (III) …

JR Shewring, AJ Cankut, LK McKenzie… - Inorganic …, 2017 - ACS Publications
We describe an Ir (III)-based small-molecule, multimodal probe for use in both light and
electron microscopy. The direct correlation of data between light-and electron-microscopy …

Engineering H2O2 Self-Supplying Platform for Xdynamic Therapies via Ru–Cu Peroxide Nanocarrier: Tumor Microenvironment-Mediated Synergistic Therapy

WB Dirersa, TC Kan, J Chang… - … Applied Materials & …, 2024 - ACS Publications
Of the most common, hypoxia, overexpressed glutathione (GSH), and insufficient H2O2
concentration in the tumor microenvironment (TME) are the main barriers to the advancment …

A phosphorescence quenching-based intelligent dissolved oxygen sensor on an optofluidic platform

F Wang, L Chen, J Zhu, X Hu, Y Yang - Micromachines, 2021 - mdpi.com
Continuous measurement of dissolved oxygen (DO) is essential for water quality monitoring
and biomedical applications. Here, a phosphorescence quenching-based intelligent …

In vitro miniaturized tuberculosis spheroid model

S Mukundan, P Singh, A Shah, R Kumar, KC O'neill… - Biomedicines, 2021 - mdpi.com
Tuberculosis (TB) is a public health concern that impacts 10 million people around the
world. Current in vitro models are low throughput and/or lack caseation, which impairs drug …

Dual Emission from Precious Metal‐Free Luminophores Consisting of C, H, O, Si, and S/P at Room Temperature

M Shimizu, S Nagano… - Chemistry–A European …, 2020 - Wiley Online Library
Fluorescence–phosphorescence dual‐emissive compounds are valuable tools for
ratiometric luminescence sensing. Herein, it is reported that 2, 5‐bis (phenylsulfonyl)‐and 2 …

Bioluminescent probe for tumor hypoxia detection via CYP450 reductase in living animals

Y Gao, Y Lin, T Liu, H Chen, X Yang, C Tian… - Analytical …, 2017 - ACS Publications
Hypoxia is a pathogenic characteristic of solid tumors owing to absent or abnormal
vasculature in the tumor microenvironment and essential in tumor progression …

Photofunctions of iridium (iii) complexes in vesicles: long-lived excited states and visible-light sensitization for hydrogen evolution in aqueous solution

S Sebata, S Takizawa, N Ikuta, S Murata - Dalton Transactions, 2019 - pubs.rsc.org
Recently, the photochemistry of cationic bis-cyclometalated Ir (III) complexes has gained
increasing attention in interdisciplinary studies owing to the characteristic photofunctions of …

Spatio-temporal monitoring of lipid peroxyl radicals in live cell studies combining fluorogenic antioxidants and fluorescence microscopy methods

LE Greene, R Lincoln, G Cosa - Free Radical Biology and Medicine, 2018 - Elsevier
Lipid peroxidation of polyunsaturated fatty acids in cells may occur via their catalytic
autoxidation through peroxyl radicals under oxidative stress conditions. Lipid peroxidation is …

Mammalian cells: A unique scaffold for in situ biosynthesis of metallic nanomaterials and biomedical applications

FU Rehman, H Jiang, M Selke, X Wang - Journal of Materials …, 2018 - pubs.rsc.org
Production of nanoscale materials often requires the use of toxic chemicals and complex
synthetic procedures. A new scaffold has been explored for in situ synthesis of …