Maternal diabetes and oocyte quality
Q Wang, KH Moley - Mitochondrion, 2010 - Elsevier
Maternal diabetes has been demonstrated to adversely affect preimplantation embryo
development and pregnancy outcomes. Emerging evidence has implicated that these effects …
development and pregnancy outcomes. Emerging evidence has implicated that these effects …
Altered meiotic regulation in oocytes from diabetic mice
SA Colton, GM Pieper, SM Downs - Biology of reproduction, 2002 - academic.oup.com
In the present study, we have utilized a streptozotocin-induced diabetic mouse model to
examine how the diabetic condition and different glucose concentrations affect several …
examine how the diabetic condition and different glucose concentrations affect several …
Prophase I arrest of mouse oocytes mediated by natriuretic peptide precursor C requires GJA1 (connexin-43) and GJA4 (connexin-37) gap junctions in the antral …
S Richard, JM Baltz - Biology of reproduction, 2014 - academic.oup.com
Fully grown germinal vesicle stage mouse oocytes remain arrested in meiotic prophase I
until ovulation. This arrest is maintained by cGMP produced in cumulus granulosa cells …
until ovulation. This arrest is maintained by cGMP produced in cumulus granulosa cells …
Energy substrates and the completion of spontaneous meiotic maturation
SM Downs, ED Hudson - Zygote, 2000 - cambridge.org
This study was carried out to examine how different combinations of pyruvate and glucose
affect spontaneous meiotic maturation of cumulus-cell-enclosed mouse oocytes (CEO) to …
affect spontaneous meiotic maturation of cumulus-cell-enclosed mouse oocytes (CEO) to …
Evolutionary interactions between diabetes and development
RG Ahmed - diabetes research and clinical practice, 2011 - Elsevier
Because of the complications of diabetes affecting the mothers and their fetus/newborns are
less known, this review examined the epidemiologic and mechanistic issues involved in the …
less known, this review examined the epidemiologic and mechanistic issues involved in the …
[HTML][HTML] Maintenance of meiotic arrest in bovine oocytes using the S-enantiomer of roscovitine: effects on maturation, fertilization and subsequent embryo …
The overall objective was to evaluate the effectiveness of the S-enantiomer of roscovitine
(inhibitor of p34 cdc2/cyclin B kinase) to maintain bovine cumulus–oocyte complexes at the …
(inhibitor of p34 cdc2/cyclin B kinase) to maintain bovine cumulus–oocyte complexes at the …
[HTML][HTML] Brefeldin A disrupts asymmetric spindle positioning in mouse oocytes
L Wang, ZB Wang, X Zhang, G FitzHarris, JM Baltz… - Developmental …, 2008 - Elsevier
Polar body formation in oocytes is an extreme form of asymmetric cell division, but what
regulates the asymmetric spindle positioning and cytokinesis is poorly understood. During …
regulates the asymmetric spindle positioning and cytokinesis is poorly understood. During …
A serotonin receptor antagonist induces oocyte maturation in both frogs and mice: Evidence that the same G protein‐coupled receptor is responsible for maintaining …
Y Sheng, L Wang, XS Liu, V Montplaisir… - Journal of cellular …, 2005 - Wiley Online Library
Accumulating evidence has indicated that vertebrate oocytes are arrested at late prophase
(G2 arrest) by a G protein coupled receptor (GpCR) that activates adenylyl cyclases …
(G2 arrest) by a G protein coupled receptor (GpCR) that activates adenylyl cyclases …
Mouse versus rat: profound differences in meiotic regulation at the level of the isolated oocyte
SM Downs - Molecular reproduction and development, 2011 - Wiley Online Library
Cumulus cell‐enclosed oocytes (CEO), denuded oocytes (DO), or dissected follicles were
obtained 44–48 hr after priming immature mice (20–23 days old) with 5 IU or immature rats …
obtained 44–48 hr after priming immature mice (20–23 days old) with 5 IU or immature rats …
Metabolism of follicles and oocytes during growth and maturation
SE Harris, HM Picton - In-Vitro Maturation of Human Oocytes …, 2007 - api.taylorfrancis.com
The current repertoire of human assisted reproduction therapies is undergoing constant
development and improvement. In-vitro maturation (IVM) of near-grown oocytes and in-vitro …
development and improvement. In-vitro maturation (IVM) of near-grown oocytes and in-vitro …