This book draws together recent data on both cytoplasmic and flagellar dyneins and the
proteins they interact with, to give readers a clear picture of what is currently known about …

Cilia are highly conserved organelles extending from almost every cell type of the human
body. Their core structure, the axoneme, consists of nine doublet microtubules composed of …

Background: The vertebrate inner ear comprises mineralized elements, namely the otoliths
(fishes) or the otoconia (mammals). These elements serve vestibular and auditory functions …

Aim: To evaluate the expression of the growth arrest-specific 8 (GAS8) and its antisense
(GAS8-AS1) in gastric cancer. Background: GAS8 exists in a genomic region that is …

Publisher Summary Eukaryotic cilia and flagella are highly conserved, microtubule-based
structures that play fundamental roles in sensory transduction and cell motility. This chapter …

Smoothened belongs to the class of atypical G protein-coupled receptors and serves as the
transducing molecule in Hedgehog (Hh) signaling. Hh proteins comprise a family of …

Abstract The multifunctional Ca 2+/calmodulin-dependent protein kinase type 2 (CaMK-II)
was first discovered in brain tissue and shown to have a central role in long term …

Los cilios son organelas celulares muy ubicuas, presentes en algún momento del desarrollo
en casi todas las células. Se han conservado durante la evolución de las especies, desde …

Proteins are essential to nearly all aspects of biology, and the synthesis of proteins from
genetic information (ie, translation) is a vital cellular process. The first step of translation is …

Background Investigations in zebrafish show that ciliation is important for the development of
the otolith organs, but this has never been evaluated in humans. PCD is a congenital defect …