Hypertension is a multifactorial disease. Although a number of different underlying
mechanisms have been learned from the various experimental models of the disease …

Recent strides in anti-cancer therapeutics have improved longevity and led to a growing
population of cancer survivors, who are increasingly likely to die of other causes. Treatment …

Inflammation is a natural defense process of the innate immune system, associated with the
release of proinflammatory cytokines such as interleukin-1β, interleukin-6, interleukin-12 …

Background and Purpose Toll‐like receptor 4 (TLR 4) signalling contributes to inflammatory
cardiovascular diseases, but its role in hypertension and the associated vascular damage is …

Hypertension is the primary cause of cardiovascular mortality. Despite multiple existing
treatments, only half of those with the disease achieve adequate control. Therefore …

Pregnancy is commonly referred to as a window into future CVH (cardiovascular health).
During pregnancy, physiological adaptations occur to promote the optimal growth and …

Regular physical activity seems to be one of the most important contributors to prevent
disease and promote health. Being physically active reduces the risk of developing chronic …

Endothelial cells (EC) are able to actively control vascular permeability, coagulation, blood
pressure and angiogenesis. Most recently, a role for endothelial cells in the immune …

Release of cell free DNA (cfDNA) from damaged or dead cells routinely occurs in normal
physiology. Recently, cfDNA has emerged as an essential biomarker in cardiovascular …

Obstructive sleep apnea (OSA) and high salt content in modern diet has been particularly
implicated in systemic hypertension, leading to increased morbidity and mortality. Gut …