Regenerative and restorative medicine for eye disease

RN Van Gelder, MF Chiang, MA Dyer, TN Greenwell… - Nature medicine, 2022 - nature.com
Causes of blindness differ across the globe; in higher-income countries, most blindness
results from the degeneration of specific classes of cells in the retina, including retinal …

Powering implantable and ingestible electronics

SY Yang, V Sencadas, SS You, NZX Jia… - Advanced functional …, 2021 - Wiley Online Library
Implantable and ingestible biomedical electronic devices can be useful tools for detecting
physiological and pathophysiological signals, and providing treatments that cannot be done …

[HTML][HTML] Celebrating the one millionth cochlear implant

FG Zeng - JASA Express Letters, 2022 - pubs.aip.org
Cochlear implants have been the most successful neural prosthesis, with one million users
globally. Researchers used the source-filter model and speech vocoder to design the …

[HTML][HTML] Retinitis pigmentosa: current clinical management and emerging therapies

XTA Nguyen, L Moekotte, AS Plomp… - International journal of …, 2023 - mdpi.com
Retinitis pigmentosa (RP) comprises a group of inherited retinal dystrophies characterized
by the degeneration of rod photoreceptors, followed by the degeneration of cone …

[HTML][HTML] Neuromorphic hardware for somatosensory neuroprostheses

E Donati, G Valle - Nature Communications, 2024 - nature.com
In individuals with sensory-motor impairments, missing limb functions can be restored using
neuroprosthetic devices that directly interface with the nervous system. However, restoring …

[HTML][HTML] Optogenetics for visual restoration: from proof of principle to translational challenges

M Lindner, MJ Gilhooley, S Hughes… - Progress in retinal and …, 2022 - Elsevier
Degenerative retinal disorders are a diverse family of diseases commonly leading to
irreversible photoreceptor death, while leaving the inner retina relatively intact. Over recent …

[HTML][HTML] Janus microparticles-based targeted and spatially-controlled piezoelectric neural stimulation via low-intensity focused ultrasound

M Han, E Yildiz, U Bozuyuk, A Aydin, Y Yu… - Nature …, 2024 - nature.com
Electrical stimulation is a fundamental tool in studying neural circuits, treating neurological
diseases, and advancing regenerative medicine. Injectable, free-standing piezoelectric …

[HTML][HTML] Advances in visual prostheses: engineering and biological challenges

E Borda, D Ghezzi - Progress in Biomedical Engineering, 2022 - iopscience.iop.org
Vision is an extraordinary sense through which we can appreciate the beauty of the world
we live in, gain invaluable knowledge and communicate with others using visual expression …

Hybrid neural autoencoders for stimulus encoding in visual and other sensory neuroprostheses

J Granley, L Relic, M Beyeler - Advances in Neural …, 2022 - proceedings.neurips.cc
Sensory neuroprostheses are emerging as a promising technology to restore lost sensory
function or augment human capabilities. However, sensations elicited by current devices …

Deep learning–based scene simplification for bionic vision

N Han, S Srivastava, A Xu, D Klein… - Proceedings of the …, 2021 - dl.acm.org
Retinal degenerative diseases cause profound visual impairment in more than 10 million
people worldwide, and retinal prostheses are being developed to restore vision to these …