MS/MS molecular networking‐guided in‐depth profiling of triterpenoid saponins from the fruit of Eleutherococcus senticosus and their neuroprotectivity evaluation

Y Zhou, YS Ren, XT Li, MT Cai, HL Li… - Phytochemical …, 2023 - Wiley Online Library
Introduction Eleutherococcus senticosus fruit (ESF) is a natural health supplement resource
that has been extensively applied as a tonic for the nervous system. The structures and …

Discovery of the Caged-Vibsane Norditerpenoids with Unprecedented Chemical Architectures and Exploration of Their Various Acid Tolerances

TM Lv, JL Han, QL Yan, B Lin, GD Yao… - The Journal of …, 2023 - ACS Publications
Cyclovibsanones A–D (1–4, respectively), featuring unprecedented caged tricyclo [5.4. 1.05,
9] dodecane and bicyclo [4.2. 1] hexane cores, were isolated from the leaves of Viburnum …

Structure elucidation of plumerubradins A–C: Correlations between 1H NMR signal patterns and structural information of [2+ 2]-type cyclobutane derivatives

Y Xiong, LJ Hu, JG Song, D Zhang, YS Peng… - Chinese Chemical …, 2024 - Elsevier
Abstract [2+ 2]-Type cyclobutane derivatives comprise a large family of natural products with
diverse molecular architectures. However, the structure elucidation of the cyclobutane ring …

A molecular networking-assisted automatic database screening strategy for comprehensive annotation of small molecules in complex matrices

XL Li, ZF Guo, XD Wen, MN Li, H Yang - Journal of Chromatography A, 2023 - Elsevier
Liquid chromatography-tandem with high-resolution mass spectrometry (LCsingle
bondHRMS) has proven challenging for annotating multiple small molecules within complex …

[HTML][HTML] New N-acylated aminoalkanoic acids from tea roots derived biocontrol agent Clonostachys rosea 15020

J Yu, Y Zhang, L Zhang, J Shi, K Wang, W Yuan… - Synthetic and Systems …, 2024 - Elsevier
Four new N-acylated aminoalkanoic acids, namely clonoroseins E− H (1− 4), together with
three previously identified analogs, clonoroseins A, B, and D (5− 7), were identified from the …

A novel strategy for the multi-components division and discovering pharmacodynamic material basis of Chinese herbal compounds: A case study of Xian-Ling-Gu-Bao …

Y Guan, B Yang, J Zeng, Y Mo, X Wu, Y Yang… - … of Pharmaceutical and …, 2024 - Elsevier
The therapeutic effects of Chinese herbal compounds are often achieved through the
synergistic interactions of multiple ingredients. However, current research predominantly …

Structurally diverse deformed phenanthrenes from Strophioblachia fimbricalyx with cytotoxic activities by inducing cell apoptosis

C Yang, H Jiang, H Mao, Y Zhang, Y Cao, Y Zhang… - Phytochemistry, 2024 - Elsevier
A group of phenanthrene derivatives with different deformed types, including four previously
undescribed derivatives (1–4), an undescribed natural product (5) and five known …

Identification and quantification of flavonoids in edible dock based on UPLC-qTOF MS/MS and molecular networking

T Jiang, X Li, H Wang, M Pi, J Hu, Z Zhu, J Zeng… - Journal of Food …, 2024 - Elsevier
Edible dock, also known as Rumex patientia L.× Rumex tianschanicus A. LOS., exhibiting
the characteristics of high yield, high protein and high nutrition, is widely used in the …

[HTML][HTML] Exploring Verrucosidin Derivatives with Glucose-Uptake-Stimulatory Activity from Penicillium cellarum Using MS/MS-Based Molecular Networking

J Han, B Chen, R Zhang, J Zhang, H Dai, T Wang… - Journal of Fungi, 2022 - mdpi.com
Under the guidance of LC-MS/MS-based molecular networking, seven new verrucosidin
derivatives, penicicellarusins AG (3–9), were isolated together with three known analogues …

[HTML][HTML] Targeted isolation of antiviral cinnamoylphloroglucinol-terpene adducts from Cleistocalyx operculatus by building blocks-based molecular networking …

J Song, R Huang, J Cai, Z Wu, L Hu, W Sun… - … Pharmaceutica Sinica B, 2024 - Elsevier
The building blocks-based molecular network (BBMN) strategy was applied to the
phytochemical investigation of Cleistocalyx operculatus, leading to the targeted isolation of …