Potential convergence of olfactory dysfunction in Parkinson's disease and COVID-19: The role of neuroinflammation

H Li, J Qian, Y Wang, J Wang, X Mi, L Qu… - Ageing Research …, 2024 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder that affects 7-10 million
individuals worldwide. A common early symptom of PD is olfactory dysfunction (OD), and …

Oral administration of sophoricoside (SOP) inhibits neuronal damage and neuroinflammation to curb neurodegeneration in Parkinson's disease

H Wang, D He, Z Li, X Gao, S Yang, M Cui, B Ye… - Chemico-Biological …, 2023 - Elsevier
Neuronal apoptosis and neuroinflammation are key factors involved in the pathological
changes of Parkinson's disease (PD). Sophoricoside (SOP) has shown anti-inflammatory …

Exploring the Efficient Natural Products for the Therapy of Parkinson's Disease via Drosophila Melanogaster (Fruit Fly) Models

W Zhang, Y Ju, Y Ren, Y Miao, Y Wang - Current Drug Targets, 2024 - ingentaconnect.com
Parkinson's disease (PD) is a severe neurodegenerative disorder, partly attributed to
mutations, environmental toxins, oxidative stress, abnormal protein aggregation, and …

Polyaspers A and B, the First Ergosterol‐Polyether Adducts with Unprecedented 6/6/6/5/5/6/6/6/6 Nonacyclic Architecture from Aspergillus sp. TJ507

H Hu, L Li, Z Shi, X Lan, Y Zhang… - Chinese Journal of …, 2024 - Wiley Online Library
Comprehensive Summary Psoriasis is a chronic immune‐mediated inflammatory skin
disease and the TNF‐α is an important therapeutic target of this disease. In our continuous …

Discovery of potential components characteristic by conjugated enone from the branches and leaves of Croton lauioides with anti-neuroinflammatory activity via …

Y Jin, Z Guo, H Zhu, Z Zhang, X Jiang, Y Yang, P Liu… - Bioorganic …, 2024 - Elsevier
In this study, the chemical composition and pharmacological activity of Croton lauioides
were investigated for the first time. The bioactive and HPLC-UV guided isolation led to the …

[HTML][HTML] Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect

M Cai, XL Bai, HJ Zang, XH Tang, Y Yan… - International Journal of …, 2023 - mdpi.com
Six new C-20 and one new C-19 quassinoids, named perforalactones FL (1–7), were
isolated from twigs of Harrisonia perforata. Spectroscopic and X-ray crystallographic …

Rational design, synthesis, and antimicrobial evaluation of novel 1, 2, 4-trizaole-substituted 1, 3, 4-oxadiazole derivatives with a dual thioether moiety

Q Fei, C Liu, Y Luo, H Chen, F Ma, S Xu, W Wu - Molecular Diversity, 2024 - Springer
In this paper, a series of novel 1, 2, 4-trizaole-substituted 1, 3, 4-oxadiazole derivatives with
a dual thioether moiety were constructed. The synthetic compounds were characterized by 1 …

Nuclear Factor Kappa B: A Nobel Therapeutic Target of Flavonoids Against Parkinson's Disease

NK Singh, A Singh - Combinatorial Chemistry & High …, 2024 - ingentaconnect.com
Parkinson's disease (PD), the most common brain-related neurodegenerative disorder, is
comprised of several pathophysiological mechanisms, such as mitochondrial dysfunction …

[PDF][PDF] 2023 年度线粒体肿瘤标志物研究进展年终盘点

席文文, 吕斌 - 中国癌症防治杂志, 2024 - zgazfz.com
2023年度线粒体肿瘤标志物研究进展年终盘点 Page 1 中国癌症防治杂志2024年2月第16卷第1期
Chin J of Oncol Prev and Treat,Feb. 2024,Vol.16,No.1 肿瘤标志物年度盘点专栏 2023年度 …

Study of Oxadiazole derivatives as precursor for multi-functional inhibitor to SARS-CoV-2: A detailed virtual screening analysis

V Kumar, S Kumar - Mongolian Journal of Chemistry, 2024 - mongoliajol.info
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is highly
contagious and has caused widespread loss of life. In the quest to find effective antiviral …