Evidence has shown that gut microbiome plays a role in modulating the development of
diseases beyond the gastrointestinal tract, including skin disorders such as psoriasis. The …

Importance Despite the growing literature on comorbidity risks in psoriasis, there remains a
critical knowledge gap on the degree to which objectively measured psoriasis severity may …

Psoriasis is a chronic inflammatory systemic disease. Evidence shows an association of
psoriasis with arthritis, depression, inflammatory bowel disease and cardiovascular …

Psoriasis is a complex inflammatory process resulting from activation of the well-defined
interleukin (IL)-23/T17 cytokine axis. We review the role of key cytokines IL-17 and IL-23 in …

Beyond classic “allergic”/atopic comorbidities, atopic dermatitis (AD) emerges as systemic
disease with increased cardiovascular risk. To better define serum inflammatory and …

Increasing epidemiological evidence suggests independent associations between psoriasis
and cardiovascular and metabolic disease. Our objective was to test the hypothesis that …

Environmental stimuli are known to contribute to psoriasis pathogenesis and that of other
autoimmune diseases, but the mechanisms are largely unknown. Here we show that the aryl …

In medical contexts, the word “phenotype” is used to refer to some deviation from normal
morphology, physiology, or behavior. The analysis of phenotype plays a key role in clinical …

Psoriasis is a systemic, immune‐mediated disorder, characterized by inflammatory skin and
joint manifestations. A range of co‐morbidities is associated with psoriasis, including …

Background Psoriasis is a common inflammatory skin disease that has been reported to be
associated with obesity. We aimed to investigate a possible causal relationship between …