The concept of psoriasis as a systemic inflammation: implications for disease management
K Reich - Journal of the European Academy of Dermatology …, 2012 - Wiley Online Library
Psoriasis is a systemic, immune‐mediated disorder, characterized by inflammatory skin and
joint manifestations. A range of co‐morbidities is associated with psoriasis, including …
joint manifestations. A range of co‐morbidities is associated with psoriasis, including …
Psoriasis and cardiovascular comorbidities: focusing on severe vascular events, cardiovascular risk factors and implications for treatment
SCS Hu, CCE Lan - International journal of molecular sciences, 2017 - mdpi.com
Psoriasis is a common and chronic inflammatory disease of the skin. It may impair the
physical and psychosocial function of patients and lead to decreased quality of life …
physical and psychosocial function of patients and lead to decreased quality of life …
Psoriasis and comorbid diseases: Implications for management
As summarized in the first article in this continuing medical education series, the currently
available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic …
available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic …
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study
A Budu-Aggrey, B Brumpton, J Tyrrell, S Watkins… - PLoS …, 2019 - journals.plos.org
Background Psoriasis is a common inflammatory skin disease that has been reported to be
associated with obesity. We aimed to investigate a possible causal relationship between …
associated with obesity. We aimed to investigate a possible causal relationship between …
Pathogenesis of chronic plaque psoriasis and its intersection with cardio-metabolic comorbidities
Psoriasis is a chronic, systemic immune-mediated disease characterized by development of
erythematous, indurated, scaly, pruritic plaques on the skin. Psoriasis is frequently …
erythematous, indurated, scaly, pruritic plaques on the skin. Psoriasis is frequently …
Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis
CT Jordan, L Cao, EDO Roberson, S Duan… - The American Journal of …, 2012 - cell.com
Psoriasis is a common inflammatory disorder of the skin and other organs. We have
determined that mutations in CARD14, encoding a nuclear factor of kappa light chain …
determined that mutations in CARD14, encoding a nuclear factor of kappa light chain …
Systemic immune mechanisms in atopic dermatitis and psoriasis with implications for treatment
E Guttman‐Yassky, JG Krueger… - Experimental …, 2018 - Wiley Online Library
Atopic dermatitis (AD) and psoriasis are inflammatory skin diseases that negatively affect
patients' quality of life. Although distinctions exist between these diseases, both are …
patients' quality of life. Although distinctions exist between these diseases, both are …
[HTML][HTML] An integrated model of atopic dermatitis biomarkers highlights the systemic nature of the disease
B Ungar, S Garcet, J Gonzalez, N Dhingra… - Journal of Investigative …, 2017 - Elsevier
Current atopic dermatitis (AD) models link epidermal abnormalities in lesional skin to
cytokine activation. However, there is evolving evidence of systemic immune activation and …
cytokine activation. However, there is evolving evidence of systemic immune activation and …
Biomarkers of disease progression in people with psoriasis: a scoping review
R Ramessur, M Corbett, D Marshall… - British Journal of …, 2022 - academic.oup.com
Background Identification of those at risk of more severe psoriasis and/or associated
morbidities offers opportunity for early intervention, reduced disease burden and more cost …
morbidities offers opportunity for early intervention, reduced disease burden and more cost …
Attributable risk estimate of severe psoriasis on major cardiovascular events
NN Mehta, YD Yu, R Pinnelas… - The American journal of …, 2011 - Elsevier
BACKGROUND: Recent studies suggest that psoriasis, particularly if severe, may be a risk
factor for major adverse cardiac events, such as myocardial infarction, stroke, and mortality …
factor for major adverse cardiac events, such as myocardial infarction, stroke, and mortality …