Identifying predictors for individuals vulnerable to the adverse effects of traumatic brain
injury (TBI) remains an ongoing research pursuit. This is especially important for patients …

Ischemia–reperfusion (I/R) injuries are from the secondary radicals of ONOO–. Direct radical
scavenging is difficult because of their high reactivity. ONOO–is longer-lived than the …

Background Increasing evidence suggests that microglia experience two distinct
phenotypes after acute ischemic stroke (AIS): a deleterious M1 phenotype and a …

Background Traumatic brain injury (TBI) is a major cause of morbidity and mortality, affecting
millions annually worldwide. Although the majority of TBI patients return to premorbid …

Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of
adult life, followed by a gradual occurrence of psychiatric disturbances, cognitive and motor …

The righting reflex (RR) is frequently used to assess level of arousal and applied to animal
models of a range of neurological disorders. RR produces a binary result that, when …

Traumatic brain injury (TBI) triggers multiple pathobiological responses with differing onsets,
magnitudes, and durations. Identifying the therapeutic window of individual pathologies is …

Closed-head concussive injury is one of the most common causes of traumatic brain injury
(TBI). Isolated concussions frequently produce acute neurological impairments, and …

Repetitive mild traumatic brain injury (r-mTBI) has increasingly become recognised as a risk
factor for the development of neurodegenerative diseases, many of which are characterised …

A major hurdle preventing effective interventions for patients with mild traumatic brain injury
(mTBI) is the lack of known mechanisms for the long-term cognitive impairment that follows …