Advances in the diagnosis and treatment of pediatric acute lymphoblastic leukemia

H Inaba, CH Pui - Journal of clinical medicine, 2021 - mdpi.com
The outcomes of pediatric acute lymphoblastic leukemia (ALL) have improved remarkably
during the last five decades. Such improvements were made possible by the incorporation of …

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

DA Arber, A Orazi, R Hasserjian… - Blood, The Journal …, 2016 - ashpublications.org
Abstract The World Health Organization (WHO) classification of tumors of the hematopoietic
and lymphoid tissues was last updated in 2008. Since then, there have been numerous …

Acute lymphoblastic leukemia in children

SP Hunger, CG Mullighan - New England Journal of Medicine, 2015 - Mass Medical Soc
Acute Lymphoblastic Leukemia in Children | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Treatment of pediatric acute lymphoblastic leukemia

SL Cooper, PA Brown - Pediatric Clinics, 2015 - pediatric.theclinics.com
Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children. It
has an overall survival of approximately 80%, with certain subsets experiencing greater than …

OF THE WORLD HEALTH ORGANIZATION CLASSIFICATION OF TUMORS OF THE HEMATOPOIETIC AND LYMPHOID TISSUES

JK Choi, W Xiao, X Chen, S Loghavi… - Modern Pathology, 2024 - Elsevier
This manuscript represents a review of lymphoblastic leukemia/lymphoma (acute
lymphoblastic leukemia/lymphoblastic lymphoma), acute leukemias of ambiguous lineage …

Pediatric acute lymphoblastic leukemia, version 2.2020, NCCN clinical practice guidelines in oncology

P Brown, H Inaba, C Annesley, J Beck… - Journal of the National …, 2020 - jnccn.org
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy.
Advancements in technology that enhance our understanding of the biology of the disease …

Impact of high-risk cytogenetics on outcomes for children and young adults receiving CD19-directed CAR T-cell therapy

AB Leahy, KJ Devine, Y Li, H Liu… - Blood, The Journal …, 2022 - ashpublications.org
Chimeric antigen receptor (CAR) T-cell therapy can induce durable remissions of
relapsed/refractory B-acute lymphoblastic leukemia (ALL). However, case reports suggested …

Genetic biomarkers and their clinical implications in B-cell acute lymphoblastic leukemia in children

M Lejman, A Chałupnik, Z Chilimoniuk… - International journal of …, 2022 - mdpi.com
Acute lymphoblastic leukemia (ALL) is a heterogeneous group of hematologic malignancies
characterized by abnormal proliferation of immature lymphoid cells. It is the most commonly …

Genomics in acute lymphoblastic leukaemia: insights and treatment implications

KG Roberts, CG Mullighan - Nature reviews Clinical oncology, 2015 - nature.com
Acute lymphoblastic leukaemia (ALL) is the commonest childhood cancer and an important
cause of morbidity from haematological malignancies in adults. In the past several years, we …

[HTML][HTML] New and emerging prognostic and predictive genetic biomarkers in B-cell precursor acute lymphoblastic leukemia

AV Moorman - Haematologica, 2016 - ncbi.nlm.nih.gov
Acute lymphoblastic leukemia (ALL) is a heterogeneous disease at the genetic level.
Chromosomal abnormalities are used as diagnostic, prognostic and predictive biomarkers to …