Targeting reprogrammed metabolism as a therapeutic approach for respiratory diseases

PXL Gan, S Zhang, WSF Wong - Biochemical Pharmacology, 2024 - Elsevier
Metabolic reprogramming underlies the etiology and pathophysiology of respiratory
diseases such as asthma, idiopathic pulmonary fibrosis (IPF), and chronic obstructive …

Blocking μ-opioid receptor by naltrexone exaggerates oxidative stress and airway inflammation via the MAPkinase pathway in a murine model of asthma

V Pandey, V Yadav, A Srivastava, P Gaglani… - Free Radical Biology …, 2024 - Elsevier
Opioids regulate various physiological and pathophysiological functions, including cell
proliferation, immune function, obesity, and neurodegenerative disorders. They have been …

Outpatient inhaled corticosteroid use in bronchopulmonary dysplasia

C Leon, A Martin, LR Young, BC Aoyama… - Pediatric …, 2024 - Wiley Online Library
Rationale In the outpatient setting, inhaled corticosteroids (ICS) are frequently given to
children with bronchopulmonary dysplasia (BPD) for treatment of respiratory and asthma …

Hexokinase 2 aggravates airway inflammation in experimental asthma by regulating airway epithelial cell death

Z Tian, S Wang, Y Fan, B Li, H Zheng, Y Lu, Z Huang… - 2024 - researchsquare.com
Background Asthma is a prevalent inflammatory lungs disease which poses a substantial
global health and economic burden. Abnormal glucose metabolism in asthmatic patients …

Outpatient Inhaled Corticosteroid Use in Bronchopulmonary Dysplasia

S McGrath-Morrow, C Leon, A Martin… - Authorea …, 2024 - essopenarchive.org
Rationale: In the outpatient setting, inhaled corticosteroids (ICS) are frequently given to
children with bronchopulmonary dysplasia (BPD) for treatment of respiratory and asthma …