MicroRNAs (miRNAs) are short sequences of non-coding RNA that play an important role in
the regulation of gene expression and thereby in many physiological and pathological …

Epigenetic phenomena are defined as heritable mechanisms that establish and maintain
mitotically stable patterns of gene expression without modifying the base sequence of DNA …

Ischemic stroke (IS) related to atherosclerosis of large arteries is one of the leading causes
of mortality and disability in developed countries. Atherosclerotic internal carotid artery …

Vascular remodelling is a multifactorial process that involves both adaptive and maladaptive
changes of the vessel wall through, among others, cell proliferation and migration, but also …

Cardiovascular disease (CVD) is a major cause of morbidity and mortality worldwide.
Innovative, more stringent diagnostic and prognostic biomarkers and effective treatment …

Approximately, 16 million strokes occur worldwide each year, causing 6 million deaths and
considerable disability, implying an enormous social, individual health, and economic …

Stroke is a leading cause of death and disability worldwide. Ischemic stroke is the dominant
subtype of stroke and results from focal cerebral ischemia due to occlusion of major cerebral …

Rationale: The interaction of circulating cells within the vascular wall is a critical event in
chronic inflammatory processes, such as atherosclerosis, but the control of the vascular …

Abstract Noncoding RNAs (long noncoding RNAs and small RNAs) are emerging as critical
modulators of phenotypic changes associated with physiological and pathological contexts …

Aims We conducted a genome-wide analysis to identify differentially methylated genes in
atherosclerotic lesions. Methods DNA methylation at promoters, exons and introns was …