Objectives This systematic review and meta-analysis investigated the association of
diabetes and glycemic control with myocardial fibrosis (MF). Background MF is associated …

Fibrosis is a common denominator in many pathologies and crucially affects disease
progression, drug delivery efficiency and therapy outcome. We here summarize therapeutic …

Background Diabetic peripheral neuropathy (DPN) has been shown to be independently
associated with cardiovascular events and mortality. This study aimed to evaluate changes …

Background Heart failure with reduced ejection fraction (HFrEF) is a major health burden
worldwide with high morbidity and mortality. Comorbidities of HFrEF complicate treatment …

Background Diffuse myocardial fibrosis and microvascular dysfunction are suggested to
underlie cardiac dysfunction in patients with type 2 diabetes, but studies investigating their …

Background Type 2 diabetes mellitus (T2DM) increases the risks of heart failure and
mortality in patients with hypertension, however the underlying mechanism is unclear. This …

OBJECTIVE Myocardial interstitial fibrosis expands the extracellular volume (ECV) and in
patients with type 2 diabetes is implicated in development of heart failure. ECV can be …

Background Coronary artery disease (CAD) confers considerable morbidity and mortality in
diabetes. However, the role of CAD in additive effect of left ventricular (LV) function has …

Background Diabetes-induced cardiac fibrosis is one of the main mechanisms of diabetic
cardiomyopathy. As a common histone methyltransferase, enhancer of zeste homolog 2 …

To evaluate variations in pre-contrast (preT1) and post-contrast (postT1) myocardial T1
values and extracellular volume fraction (ECV) according to left ventricular (LV) segments …