High-dose intravenous vitamin C, a promising multi-targeting agent in the treatment of cancer

F Böttger, A Vallés-Martí, L Cahn… - Journal of experimental & …, 2021 - Springer
Mounting evidence indicates that vitamin C has the potential to be a potent anti-cancer
agent when administered intravenously and in high doses (high-dose IVC). Early phase …

Understanding the therapeutic potential of ascorbic acid in the battle to overcome cancer

J Reang, PC Sharma, VK Thakur, J Majeed - Biomolecules, 2021 - mdpi.com
Cancer, a fatal disease, is also one of the main causes of death worldwide. Despite various
developments to prevent and treat cancer, the side effects of anticancer drugs remain a …

Microfluidic gradient culture arrays for cell pro-oxidation analysis using bipolar electrochemiluminescence

Y Liu, QY Cheng, H Gao, HY Chen, JJ Xu - Analytical Chemistry, 2023 - ACS Publications
A microfluidic gradient array is a widely used screening and analysis device, which has
characteristics of high efficiency, high automation, and low consumption. Bipolar electrode …

Pharmacological vitamin C inhibits mTOR signaling and tumor growth by degrading Rictor and inducing HMOX1 expression

S Qin, G Wang, L Chen, H Geng, Y Zheng, C Xia… - PLoS …, 2023 - journals.plos.org
Pharmacological vitamin C (VC) is a potential natural compound for cancer treatment.
However, the mechanism underlying its antitumor effects remains unclear. In this study, we …

A history of targeted therapy development and progress in novel–novel combinations for chronic lymphocytic leukemia (CLL)

M Karr, L Roeker - Cancers, 2023 - mdpi.com
Simple Summary The treatment landscape for CLL has changed dramatically since the
advent of targeted therapies. Studies have shown clear progression-free survival (PFS) …

Restoration of the immune function as a complementary strategy to treat chronic lymphocytic leukemia effectively

C Moreno, C Muñoz, MJ Terol… - Journal of Experimental …, 2021 - Springer
Abstract Chronic Lymphocytic Leukemia (CLL) is a hematological malignancy characterized
by uncontrolled proliferation of B-cells and severe immune dysfunction. Chemo (immuno) …

Ascorbyl palmitate: A comprehensive review on its characteristics, synthesis, encapsulation and applications

M Imran, B Titilayo, M Adil, Q Mehmood, SH Mustafa… - Process …, 2024 - Elsevier
Ascorbyl palmitate, commonly known as Vitamin C ester or Vitamin C palmitate in the food
industry is an ester derivative of ascorbic acid. It is produced through an esterification …

Apoptosis, a Metabolic “Head-to-Head” between Tumor and T Cells: Implications for Immunotherapy

O Franzese, P Ancona, N Bianchi, G Aguiari - Cells, 2024 - mdpi.com
Induction of apoptosis represents a promising therapeutic approach to drive tumor cells to
death. However, this poses challenges due to the intricate nature of cancer biology and the …

The pseudocapacitance and sensing materials constructed by Dawson/basket-like phosphomolybdate

LL He, LP Cui, K Yu, JH Lv, YJ Ma, R Tian… - Journal of Solid State …, 2022 - Elsevier
Three phosphomolybdate hybrid derivatives,(H 2 bib) 2.5 {HP 2 Mo 18 O 62}· 2H 2 O (1),(H
2 bib){Sr⊂ H 4 P 6 Mo 18 O 73}· 6H 2 O (2),(H 2 bib) 3 [{Co (H 2 O) 2}{Sr⊂ P 6 Mo 16 Ⅵ Mo …

[HTML][HTML] Vitamin C Supplementation in the Treatment of Autoimmune and Onco-Hematological Diseases: From Prophylaxis to Adjuvant Therapy

S Isola, L Gammeri, F Furci, S Gangemi… - International Journal of …, 2024 - mdpi.com
Vitamin C is a water-soluble vitamin introduced through the diet with anti-inflammatory,
immunoregulatory, and antioxidant activities. Today, this vitamin is integrated into the …