[HTML][HTML] Lipoprotein (a) beyond the kringle IV repeat polymorphism: the complexity of genetic variation in the LPA gene
S Coassin, F Kronenberg - Atherosclerosis, 2022 - Elsevier
Abstract High lipoprotein (a)[Lp (a)] concentrations are one of the most important genetically
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
determined risk factors for cardiovascular disease. Lp (a) concentrations are an enigmatic …
Pathobiology of Lp (a) in calcific aortic valve disease
P Mathieu, BJ Arsenault, MC Boulanger… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Calcific aortic valve disease (CAVD) is the most prevalent heart valve disorder.
Gene variant in the LPA gene, which encodes for apolipoprotein (a), has been associated at …
Gene variant in the LPA gene, which encodes for apolipoprotein (a), has been associated at …
Comprehensive Analysis of Genomic Variation in the LPA Locus and Its Relationship to Plasma Lipoprotein(a) in South Asians, Chinese, and European Caucasians
Background—Functional copy number variation in the apolipoprotein (a) gene (LPA)
underlies a variable number of protein kringle domains repeated in tandem in the lipoprotein …
underlies a variable number of protein kringle domains repeated in tandem in the lipoprotein …
[HTML][HTML] The kringle IV type 2 domain variant 4925G> A causes the elusive association signal of the LPA pentanucleotide repeat
R Grüneis, H Weissensteiner, C Lamina… - Journal of Lipid …, 2022 - ASBMB
Abstract Lipoprotein (a)[Lp (a)] concentrations are regulated by the LPA gene mainly via the
large kringle IV-type 2 (KIV-2) copy number variation and multiple causal variants. Early …
large kringle IV-type 2 (KIV-2) copy number variation and multiple causal variants. Early …
[HTML][HTML] The effect of LPA Thr3888Pro on lipoprotein (a) and coronary artery disease is modified by the LPA KIV-2 variant 4925G> A
R Grüneis, C Lamina, S Di Maio, S Schönherr… - Atherosclerosis, 2022 - Elsevier
Background and aims High lipoprotein (a)[Lp (a)] concentrations are associated with
increased coronary artery disease (CAD) risk. Lp (a) is regulated mainly genetically by the …
increased coronary artery disease (CAD) risk. Lp (a) is regulated mainly genetically by the …
Research advances in the influence of lipid metabolism on cognitive impairment
M Zhang, YH Zhu, ZQ Zhu - Ibrain, 2024 - Wiley Online Library
Cognitive impairment (CI) is a mental disorder related to cognition and understanding, which
is mainly categorized into mild CI and senile dementia. This disease is associated with …
is mainly categorized into mild CI and senile dementia. This disease is associated with …