Compulsive behaviour, an apparently irrational perseveration in often maladaptive acts, is a
potential transdiagnostic symptom of several neuropsychiatric disorders, including …

Achieving abstinence from drugs is a long journey and can be particularly challenging in the
case of methamphetamine, which has a higher relapse rate than other drugs. Therefore, real …

Aims The orbitofrontal cortex (OFC) is implicated in compulsive drug-seeking and relapse,
the characteristics that result in addiction treatment failure. Structural and functional …

Objective Although previous studies have discussed the promise of deep brain stimulation
(DBS) as a possible treatment for substance use disorders (SUDs) and collected researcher …

Crack-cocaine dependence is a severe condition with a high mortality rate. This single case
study report details the first deep brain stimulation (DBS) trial targeting the sub-thalamic …

Abstract Compassion Focused Therapy (CFT) targets underlying shame and self-criticism to
shift one's style of self-relating and capacity to engage with a soothing-affiliate mode. CFT …

It has been shown that high-frequency deep brain stimulation (DBS) of the lateral
hypothalamus (LH) prevents morphine-induced conditioned place preference (CPP) in rats …

The nucleus accumbens (NAc) and the anterior limb of internal capsule (ALIC) are effective
targets for treating addiction using deep brain stimulation (DBS). However, there have been …

We have previously shown that high-frequency deep brain stimulation (DBS) of the lateral
hypothalamus (LH) compromises morphine-induced addiction-like behavior in rats. The …

Limbic surgery is one of the most attractive and retaken fields of functional neurosurgery in
the last two decades. Psychiatric surgery emerged from the incipient work of Moniz and Lima …