The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …

Matrix stiffness is a mechanical characteristic of the extracellular matrix (ECM) that increases
from the tumor core to the tumor periphery in a gradient pattern in a variety of solid tumors …

Stitched fluorescence microscope images inevitably exist in various types of stripes or
artifacts caused by uncertain factors such as optical devices or specimens, which severely …

Background Gastrointestinal stromal tumor (GIST) is currently regarded as a potentially
malignant tumor, and early diagnosis is the best way to improve its prognosis. Therefore, it …

Ductal carcinoma in situ with microinvasion (DCISM) is a challenging subtype of breast
cancer with controversial invasiveness and prognosis. Accurate diagnosis of DCISM from …

Breast cancer is a significant global health burden, causing a substantial number of deaths.
Systemic metastatic tumour cell dissemination is a major cause of poor outcomes …

Epithelial ovarian cancer (EOC) is often diagnosed in advanced stage with peritoneal
dissemination. Recent studies indicate that aberrant accumulation of collagen fibers in tumor …

摘要长期以来, 乳腺癌的发病率占据全球女性恶性肿瘤发病率的首位. 国际癌症研究机构最新
发布的2020 年全球癌症负担数据显示, 乳腺癌在全球发病数超过了肺癌, 成为全球第一大癌 …

We investigated how the extracellular matrix (ECM) affects LoVo colorectal cancer cells
behavior during a spatiotemporal invasion. Epithelial-to-mesenchymal transition (EMT) …

Neoadjuvant treatment is often considered in breast cancer patients with axillary lymph node
involvement, but most of patients do not have a pathologic complete response to therapy …