Abstract Purpose of Review The polycystic ovary syndrome (PCOS) is an endocrine
dysfunction associated with a myriad of metabolic disorders and high rate of infertility. In …

Chronic kidney disease (CKD) is prevalent in 9.1% of the global population and is a
significant public health problem associated with increased morbidity and mortality. CKD is …

The sterol regulatory element-binding protein (SREBP) transcription factor family is a critical
regulator of lipid and sterol homeostasis in eukaryotes. In mammals, SREBPs are highly …

The modulation of macroautophagy is now recognized as one of the hallmarks of cancer
cells. There is accumulating evidence that autophagy plays a role in the various stages of …

The endothelium, although only a single layer of cells lining the vascular and lymphatic
systems, contributes in multiple ways to vascular homeostasis. Subsequent to the 1980 …

Polycystic ovary syndrome (PCOS) is a commonly occurring endocrine disorder
characterized by hirsutism, anovulation, and polycystic ovaries. Often comorbid with insulin …

Resveratrol is a polyphenol that is mainly found in grapes and red wine and has been
reported to be a caloric restriction (CR) mimetic driven by Sirtuin 1 (SIRT1) activation …

It has been demonstrated in rodents and humans that chronic inflammation characterized by
macrophage infiltration occurs mainly in adipose tissue or liver during obesity, in which …

This study examined the hypothesis that vitamin-D prevents oxidative stress and
upregulates glucose metabolism via activating insulin-independent signaling molecules in …

Age-related macular degeneration is a major cause of vision impairment in the Western
world among people of 55 years and older. Recently we have shown that autophagy is …