Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …

Glucose metabolism is the initiator of a large number of molecular secretory processes in β
cells. Cyclic nucleotides as a second messenger are the main physiological regulators of …

A failure in immune tolerance leads to autoimmune destruction of insulin-producing β-cells,
leading to type 1 diabetes (T1D). Inhibiting autoreactive T cells and inducing regulatory T …

Type 1 diabetes (T1D) is an incurable condition with an increasing incidence worldwide, in
which the hallmark is the autoimmune destruction of pancreatic insulin-producing β cells …

Pancreatic islet cells, and in particular insulin-producing beta cells, are centrally involved in
the pathogenesis of diabetes mellitus. These cells are of paramount importance for the …

The coupling of phenylboronic acids with poorly‐activated imidazoles is studied as a model
system to explore the use of copper‐catalyzed Chan–Evans–Lam (CEL) coupling for …

Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction
of insulin-producing β-cells of the pancreatic islets by autoreactive T cells, leading to high …

Type 1 diabetes mellitus (T1DM) is an autoimmune disease that targets the destruction of
islet beta-cells resulting in insulin deficiency, hyperglycemia and death if untreated. Despite …

Abstract Type 1 Diabetes Mellitus (T1DM) is characterized by progressive autoimmune-
mediated destruction of the pancreatic beta-cells leading to insulin deficiency and …

Induced pluripotent stem cells (iPSC) represent a potentially exciting regenerative-medicine
cell therapy for several chronic conditions such as macular degeneration, soft tissue and …