[HTML][HTML] Prospective multifunctional roles and pharmacological potential of dietary flavonoid narirutin

S Mitra, MS Lami, TM Uddin, R Das, F Islam… - Biomedicine & …, 2022 - Elsevier
Plant-based phytochemicals are now being used to treat plenty of physiological diseases.
Herbal drugs have gained popularity in recent years because of their strength, purity, and …

The role of p53 signaling in colorectal cancer

MC Liebl, TG Hofmann - Cancers, 2021 - mdpi.com
Simple Summary The transcription factor p53 is a crucial tumor suppressor that regulates
diverse cellular responses to protect against cancer development. Deactivating p53 …

Anticancer Activity of Rosmarinus officinalis L.: Mechanisms of Action and Therapeutic Potentials

A Allegra, A Tonacci, G Pioggia, C Musolino… - Nutrients, 2020 - mdpi.com
Alternative treatments for neoplastic diseases with new drugs are necessary because the
clinical effectiveness of chemotherapy is often reduced by collateral effects. Several natural …

A mechanistic insight into the biological activities of urolithins as gut microbial metabolites of ellagitannins

SH Hasheminezhad, M Boozari… - Phytotherapy …, 2022 - Wiley Online Library
Urolithins are the gut metabolites produced from ellagitannin‐rich foods such as
pomegranates, tea, walnuts, as well as strawberries, raspberries, blackberries, and …

NAT10 mediated mRNA acetylation modification patterns associated with colon cancer progression and microsatellite status

H Zhang, W Shan, Z Yang, Y Zhang, M Wang, L Gao… - Epigenetics, 2023 - Taylor & Francis
ABSTRACT N4-acetylcytidine (ac4C) is one type of RNA modification found in eukaryotes.
RNA acetylation modifications are gradually expanding in oncology. However, the role of …

A comprehensive survey of intestine histopathological image analysis using machine vision approaches

Y Jing, C Li, T Du, T Jiang, H Sun, J Yang, L Shi… - Computers in Biology …, 2023 - Elsevier
Colorectal Cancer (CRC) is currently one of the most common and deadly cancers. CRC is
the third most common malignancy and the fourth leading cause of cancer death worldwide …

Targeting Farnesoid X receptor (FXR) for developing novel therapeutics against cancer

S Girisa, S Henamayee, D Parama, V Rana… - Molecular …, 2021 - Springer
Cancer is one of the lethal diseases that arise due to the molecular alterations in the cell.
One of those alterations associated with cancer corresponds to differential expression of …

Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia

CR Gurbatri, GA Radford, L Vrbanac, J Im… - Nature …, 2024 - nature.com
Bioengineered probiotics enable new opportunities to improve colorectal cancer (CRC)
screening, prevention and treatment. Here, first, we demonstrate selective colonization of …

Recent advancements, limitations, and future perspectives of the use of personalized medicine in treatment of colon cancer

A Dey, A Mitra, S Pathak, S Prasad… - … in Cancer Research …, 2023 - journals.sagepub.com
Due to the heterogeneity of colon cancer, surgery, chemotherapy, and radiation are
ineffective in all cases. The genomic profile and biomarkers associated with the process are …

[HTML][HTML] ER stress activates TAp73α to promote colon cancer cell apoptosis via the PERK-ATF4 pathway

S Sun, Y Yi, ZXJ Xiao, H Chen - Journal of Cancer, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the fourth most diagnosed cancer worldwide. 43% of CRCs
harbor p53 mutations. The tumor suppressor p53 induces cell growth arrest and/or …