[HTML][HTML] Allicin, an antioxidant and neuroprotective agent, ameliorates cognitive impairment

MS Nadeem, I Kazmi, I Ullah, K Muhammad, F Anwar - Antioxidants, 2021 - mdpi.com
Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

[HTML][HTML] Inflammation and oxidative stress: potential targets for improving prognosis after subarachnoid hemorrhage

F Wu, Z Liu, G Li, L Zhou, K Huang, Z Wu… - Frontiers in cellular …, 2021 - frontiersin.org
Subarachnoid hemorrhage (SAH) has a high mortality rate and causes long-term disability
in many patients, often associated with cognitive impairment. However, the pathogenesis of …

[HTML][HTML] Anti-inflammatory effects of flavonoids in common neurological disorders associated with aging

H Martínez-Coria, I Arrieta-Cruz… - International journal of …, 2023 - mdpi.com
Aging reduces homeostasis and contributes to increasing the risk of brain diseases and
death. Some of the principal characteristics are chronic and low-grade inflammation, a …

[HTML][HTML] The association between oral and gut microbiota in male patients with alcohol dependence

L Hu, Z Ni, K Zhao, X Li, X Gao, Y Kang, Z Yu… - Frontiers in …, 2023 - frontiersin.org
Introduction The relationship between oral and gut microbiota in alcohol dependence (AD)
is not well understood, particularly the effects of oral microbiota on the intestinal microbiota …

[HTML][HTML] Toll-like receptors and NLRP3 inflammasome-dependent pathways in Parkinson's disease: mechanisms and therapeutic implications

L Soraci, ME Gambuzza, L Biscetti, P Laganà… - Journal of …, 2023 - Springer
Parkinson's disease (PD) is a chronic progressive neurodegenerative disorder
characterized by motor and non-motor disturbances as a result of a complex and not fully …

[HTML][HTML] Ethanol induces neuroinflammation in a chronic plus binge mouse model of alcohol use disorder via TLR4 and MyD88-dependent signaling

KN Holloway, JC Douglas, TM Rafferty, CJM Kane… - Cells, 2023 - mdpi.com
Ethanol induces neuroinflammation, which is believed to contribute to the pathogenesis of
alcohol use disorder (AUD). Toll-like receptors (TLRs) are a group of pattern recognition …

[HTML][HTML] Alcohol and the brain–gut axis: the involvement of microglia and enteric glia in the process of neuro-enteric inflammation

MAS Khan, SL Chang - Cells, 2023 - mdpi.com
Binge or chronic alcohol consumption causes neuroinflammation and leads to alcohol use
disorder (AUD). AUD not only affects the central nervous system (CNS) but also leads to …

Stress-induced neuroinflammation of the spinal cord is restrained by Cort113176 (Dazucorilant), a specific glucocorticoid receptor modulator

M Meyer, O Meijer, H Hunt, J Belanoff, A Lima… - Molecular …, 2024 - Springer
Glucocorticoids exert antiinflammatory, antiproliferative and immunosupressive effects.
Paradoxically they may also enhance inflammation particularly in the nervous system, as …

Emerging evidence for endogenous neurosteroid modulation of pro-inflammatory and anti-inflammatory pathways that impact neuropsychiatric disease

AL Morrow, G Boero, I Balan - Neuroscience & Biobehavioral Reviews, 2024 - Elsevier
This mini-review presents emerging evidence that endogenous neurosteroids modulate
both pro-and anti-inflammatory signaling by immune cells and brain cells that contribute to …

[HTML][HTML] Multidirectional associations between the gut microbiota and Parkinson's disease, updated information from the perspectives of humoral pathway, cellular …

X Jia, Q Chen, Y Zhang, T Asakawa - Frontiers in Cellular and …, 2023 - frontiersin.org
The human gastrointestinal tract is inhabited by a diverse range of microorganisms,
collectively known as the gut microbiota, which form a vast and complex ecosystem. It has …