▪ Abstract Interrogation of tissue with light offers the potential for noninvasive chemical
measurement, and penetration with near-infrared wavelengths (750–1000 nm) is greater …

In conclusion, NIRS appears to offer both a new monitoring modality and new information
about cerebral oxygenation. Technical problems in the application of this technology persist …

In near–infrared spectroscopy (NIRS) of tissue, light attenuation is due to:(i) absorption from
chromophores of fixed concentration,(ii) absorption from chromophores of variable …

A new clinical tissue oxygenation monitor, the NIRO-300, has been developed. In addition to
monitoring changes in hemoglobin concentration and redox state of cytochrome oxidase …

Near-infrared light propagation in various models of the adult head is analyzed by both time-
of-flight measurements and mathematical prediction. The models consist of three-or four …

We have used continuous-wave (CW) and frequency-domain spectroscopy to investigate
the optical properties of the newborn piglet brain in vivo and non-invasively. Three …

Background and Purpose—The clinical application of intracranial near-infrared
spectroscopy in adults has been hampered by concerns over contamination from …

Currently available tomographic image reconstruction schemes for optical tomography (OT)
are mostly based on the limiting assumptions of small perturbations and a priori knowledge …

We have experimentally investigated the meaning of the effective optical absorption
[μ_a^(eff)] and the reduced scattering [μ_s′^(eff)] coefficients measured on the surfaces of …

We report on the development of an iterative image reconstruction scheme for optical
tomography that is based on the equation of radiative transfer. Unlike the commonly applied …