[HTML][HTML] Sequencing-based transcriptome analysis reveals diversification of immune response-and angiogenesis-related expression patterns of early-stage cervical …

OV Kurmyshkina, PV Dobrynin, PI Kovchur… - Frontiers in …, 2023 - frontiersin.org
Background Molecular diversity of virus-associated cervical cancer remains a relatively
underexplored issue, and interrelations of immunologic and angiogenic features during the …

[HTML][HTML] Visceral fat percentage for prediction of outcome in uterine cervical cancer

AJ Eide, MK Halle, N Lura, KE Fasmer… - Gynecologic …, 2023 - Elsevier
Objective The prognostic role of adiposity in uterine cervical cancer (CC) is largely unknown.
Abdominal fat distribution may better reflect obesity than body mass index. This study aims …

[HTML][HTML] Radiomic profiles improve prognostication and reveal targets for therapy in cervical cancer

MK Halle, E Hodneland, KS Wagner-Larsen… - Scientific Reports, 2024 - nature.com
Cervical cancer (CC) is a major global health problem with 570,000 new cases and 266,000
deaths annually. Prognosis is poor for advanced stage disease, and few effective treatments …

Pancancer Analysis of Revealed TDO2 as a Biomarker of Prognosis and Immunotherapy

J Cui, Y Tian, T Liu, X Lin, L Li, Z Li, L Shen - Disease Markers, 2022 - Wiley Online Library
Background. Tryptophan 2, 3‐dioxygenase (TDO) encoded by TDO2, a rate‐limiting enzyme
in the kynurenine pathway, catabolizes tryptophan to kynurenine, evades immune …

Identification of immune and hypoxia risk classifier to estimate immune microenvironment and prognosis in cervical cancer

Y Shi, Q Gao, Z Liu, G Shen, X Sun, X Di - Journal of Oncology, 2022 - Wiley Online Library
Purpose. Cervical cancer (CC) is one of the most common gynecologic neoplasms. Hypoxia
is an essential trigger for activating immunosuppressive activity and initiating malignant …

[HTML][HTML] Low-Grade Cervical Intraepithelial Neoplasia (CIN1) Evolution: Analysis of Opportunistic Preventive Vaccination Role

B Gardella, M Dominoni, MF Pasquali, C Melito… - Vaccines, 2023 - mdpi.com
Background: Low-grade cervical lesions have a high percentage of clearance in young
women, even if 71–82% of low-grade intraepithelial lesion/atypical squamous cells of …

[HTML][HTML] Evaluation of CIN2/3 Lesion Regression in GynTect® DNA Methylation-Marker-Negative Patients in a Longitudinal Study

H Hoyer, C Stolte, G Böhmer, M Hampl, I Hagemann… - Cancers, 2023 - mdpi.com
Simple Summary Precancerous cervical lesions, especially among young women, are
frequently cleared by the immune system. Consequently, immediate surgical treatment is not …

Development Immune-Related Prognostic Model and LncRNA-miRNA-mRNA ceRNA Network for Cervical Cancer

H Xu, J Zhao, T Zhang, Y Gao, C Shi - Russian Journal of Genetics, 2024 - Springer
Cervical cancer is a serious threat to women's health. The aim of this study was to provide
new insights into the mechanism of cervical cancer by constructing immune-related …

Транскриптомный RNA-SEQ анализ опухолевого микроокружения: на пути к разработке молекулярной классификации вирус-ассоциированного …

ОВ Курмышкина, ПИ Ковчур… - Злокачественные …, 2023 - malignanttumors.org
Аннотация Молекулярно-генетическое и иммунное разнообразие вирус-
ассоциированного рака шейки матки представляет сравнительно малоисследованную …

Necroptosis-associated long noncoding RNA predicts prognosis for cervical cancer in a microenvironment signature associated with anti-tumor immune responses

J Yang, Z Ma, H Yu, Y Zhang - 2023 - researchsquare.com
Background: Cancer has high incidence rate, poor prognosis and high intratumoral
heterogeneity. Necrosis is an important cellular signaling pathway in tumor cells, which can …