Post-acute COVID-19 syndrome

D Montani, L Savale, N Noel… - European …, 2022 - Eur Respiratory Soc
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the coronavirus disease 2019 (COVID-19) pandemic that has resulted in …

Long COVID: mechanisms, risk factors and recovery

R Astin, A Banerjee, MR Baker, M Dani… - Experimental …, 2023 - Wiley Online Library
Long COVID, the prolonged illness and fatigue suffered by a small proportion of those
infected with SARS‐CoV‐2, is placing an increasing burden on individuals and society. A …

Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts

JW Guarnieri, JM Dybas, H Fazelinia, MS Kim… - Science translational …, 2023 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …

Unraveling the mystery surrounding post-acute sequelae of COVID-19

RK Ramakrishnan, T Kashour, Q Hamid… - Frontiers in …, 2021 - frontiersin.org
More than one year since its emergence, corona virus disease 2019 (COVID-19) is still
looming large with a paucity of treatment options. To add to this burden, a sizeable subset of …

Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome

BD Paul, MD Lemle, AL Komaroff… - Proceedings of the …, 2021 - National Acad Sciences
Although most patients recover from acute COVID-19, some experience postacute sequelae
of severe acute respiratory syndrome coronavirus 2 infection (PASC). One subgroup of …

The neurological manifestations of post-acute sequelae of SARS-CoV-2 infection

N Moghimi, M Di Napoli, J Biller, JE Siegler… - Current Neurology and …, 2021 - Springer
Abstract Purpose of Review Coronavirus disease 2019 (COVID-19), caused by the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global health challenge. This …

A review of cytokine-based pathophysiology of Long COVID symptoms

RN Low, RJ Low, A Akrami - Frontiers in Medicine, 2023 - frontiersin.org
The Long COVID/Post Acute Sequelae of COVID-19 (PASC) group includes patients with
initial mild-to-moderate symptoms during the acute phase of the illness, in whom recovery is …

T cell metabolism in infection

JA Wik, BS Skålhegg - Frontiers in immunology, 2022 - frontiersin.org
T lymphocytes (T cells) are divided into two functionally different subgroups the CD4+ T
helper cells (Th) and the CD8+ cytotoxic T lymphocytes (CTL). Adequate CD4 and CD8 T …

Innate metabolic responses against viral infections

CS Palmer - Nature Metabolism, 2022 - nature.com
Metabolic adaptation to viral infections critically determines the course and manifestations of
disease. At the systemic level, a significant feature of viral infection and inflammation that …

Long COVID: a review and proposed visualization of the complexity of long COVID

R Perumal, L Shunmugam, K Naidoo… - Frontiers in …, 2023 - frontiersin.org
Post-Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus–2 (SARS-CoV-2)
infection, or Long COVID, is a prevailing second pandemic with nearly 100 million affected …