Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): a review of clinical and MRI features, diagnosis, and management

E Sechi, L Cacciaguerra, JJ Chen, S Mariotto… - Frontiers in …, 2022 - frontiersin.org
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is the
most recently defined inflammatory demyelinating disease of the central nervous system …

International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

DM Wingerchuk, B Banwell, JL Bennett, P Cabre… - Neurology, 2015 - AAN Enterprises
Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple
sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies …

MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: epidemiology, clinical presentation, radiological and laboratory features, treatment …

S Jarius, K Ruprecht, I Kleiter, N Borisow… - Journal of …, 2016 - Springer
Background A subset of patients with neuromyelitis optica spectrum disorders (NMOSD) has
been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies (MOG …

MRI characteristics of neuromyelitis optica spectrum disorder: an international update

HJ Kim, F Paul, MA Lana-Peixoto, S Tenembaum… - Neurology, 2015 - AAN Enterprises
Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to
involve only the optic nerves and spinal cord. However, the discovery of highly specific anti …

Optic neuritis

AT Toosy, DF Mason, DH Miller - The Lancet Neurology, 2014 - thelancet.com
Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Neuromyelitis optica spectrum disorders with aquaporin-4 and myelin-oligodendrocyte glycoprotein antibodies: a comparative study

J Kitley, P Waters, M Woodhall, MI Leite… - JAMA …, 2014 - jamanetwork.com
Importance Most patients with neuromyelitis optica (NMO) and many with NMO spectrum
disorder have autoantibodies against aquaporin-4 (AQP4-Abs), but recently, myelin …

Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS)

C Trebst, S Jarius, A Berthele, F Paul, S Schippling… - Journal of …, 2014 - Springer
Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

Optic neuritis

JL Bennett - Continuum: lifelong learning in neurology, 2019 - journals.lww.com
PURPOSE OF REVIEW This article discusses the clinical presentation, evaluation, and
management of the patient with optic neuritis. Initial emphasis is placed on clinical history …

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients

S Jarius, K Ruprecht, B Wildemann, T Kuempfel… - Journal of …, 2012 - Springer
Background The diagnostic and pathophysiological relevance of antibodies to aquaporin-4
(AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been …

Physiological roles of aquaporin-4 in brain

EA Nagelhus, OP Ottersen - Physiological reviews, 2013 - journals.physiology.org
Aquaporin-4 (AQP4) is one of the most abundant molecules in the brain and is particularly
prevalent in astrocytic membranes at the blood-brain and brain-liquor interfaces. While …