[HTML][HTML] Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation

JE Schoenhals, SN Seyedin, C Anderson… - … lung cancer research, 2017 - ncbi.nlm.nih.gov
The study of immunology has led to breakthroughs in treating non-small cell lung cancer
(NSCLC). The recent approval of an anti-PD1 checkpoint drug for NSCLC has generated …

[HTML][HTML] The diagnostic and prognostic value of interleukin-6 in patients with soft tissue sarcomas

T Hagi, T Nakamura, T Iino, T Matsubara… - Scientific Reports, 2017 - nature.com
The presence of systemic inflammation has been reported to be associated with poor
prognosis in patients with soft tissue sarcoma (STS). The cytokine interleukin-6 (IL-6) has …

Comprehensive Review of Bioactive and Molecular Aspects of Moringa Oleifera Lam

KH Shah, MJ Oza - Food Reviews International, 2022 - Taylor & Francis
Moringa oleifera Lam. is a multi-purpose perennial plant belonging to family Moringaceae.
Traditionally, it has been used to cure diabetes, anaemia, asthma, typhoid fever, arthritis …

Rheumatologic diseases impact the risk of progression of MGUS to overt multiple myeloma

N Steiner, G Göbel, D Michaeler, AL Platz… - Blood …, 2021 - ashpublications.org
Monoclonal gammopathy of undetermined significance (MGUS), a premalignant condition,
is associated with various chronic inflammatory rheumatic diseases (RDs) and is frequently …

[HTML][HTML] The tree shrew as a model for cancer research

T Lu, H Peng, L Zhong, P Wu, J He, Z Deng… - Frontiers in …, 2021 - frontiersin.org
Animal disease models are necessary in medical research, and an appropriate animal
model is of great importance for studies about the prevention or treatment of cancer. The …

[HTML][HTML] A mendelian randomization study investigates the causal relationship between immune cell phenotypes and cerebral aneurysm

X Shi, T Wang, D Teng, S Hou, N Lin - Frontiers in Genetics, 2024 - frontiersin.org
Background: Cerebral aneurysms (CAs) are a significant cerebrovascular ailment with a
multifaceted etiology influenced by various factors including heredity and environment. This …

[HTML][HTML] Expression of interleukin-6 and the interleukin-6 receptor predicts the clinical outcomes of patients with soft tissue sarcomas

K Nakamura, T Nakamura, T Iino, T Hagi, K Kita… - Cancers, 2020 - mdpi.com
Interleukin-6 (IL-6) affects the key parameters of oncogenesis, which increases the cell
resistance to apoptosis, the proliferation of cancer cells, angiogenesis, invasion …

Inflammasomes in breast cancer: the ignition spark of progression and resistance?

S Elgohary, HM El Tayebi - Expert Reviews in Molecular Medicine, 2023 - cambridge.org
Inflammation and immune evasion are major key players in breast cancer (BC) progression.
Recently, the FDA approved the use of anti-programmed death-ligand 1 antibody (anti-PD …

[HTML][HTML] The cargo protein MAP17 (PDZK1IP1) regulates the immune microenvironment

JM García-Heredia, A Carnero - Oncotarget, 2017 - ncbi.nlm.nih.gov
Inflammation is a complex defensive response activated after various harmful stimuli
allowing the clearance of damaged cells and initiating healing and regenerative processes …

Exposure of nonylphenol promoted NLRP3 inflammasome and GSDMD-mediated pyroptosis in allergic rhinitis mice

Y Wang, H Zhao, J Yang, Z Cao, L Hao, Z Gu - Food and Chemical …, 2024 - Elsevier
Studies have confirmed that the intake of nonylphenol (NP) can increase nasal symptoms,
eosinophils, and Th2 responses in allergic rhinitis (AR) mice. However, the molecular …