Resistance of important bacterial pathogens to common antimicrobial therapies and the
emergence of multidrug-resistant bacteria are increasing at an alarming rate and constitute …

The injectisome type three secretion system (T3SS) is a major virulence factor in
Pseudomonas aeruginosa. This bacterium is responsible for severe infections in …

Infections with Pseudomonas aeruginosa have become a concerning threat in hospital-
acquired infections and for cystic fibrosis patients. The major problem leading to high …

Targeting the virulence factors of phytopathogenic bacteria is an innovative strategy for
alleviating or eliminating the pathogenicity and rapid outbreak of plant microbial diseases …

The recent and dramatic rise of antibiotic resistance among bacterial pathogens underlies
the fear that standard treatments for infectious disease will soon be largely ineffective …

Salmonella enterica is an important foodborne pathogen that uses secreted effector proteins
to manipulate host pathways to facilitate survival and dissemination. Different S. enterica …

Pathogenic Yersinia species suppress the host immune response by using a plasmid-
encoded type III secretion system (T3SS) to translocate virulence proteins into the cytosol of …

The elucidation of the molecular mechanisms of secretion through bacterial protein
secretion systems is impeded by a shortage of assays to quantitatively assess secretion …

Inhalation of Yersinia pestis causes primary pneumonic plague, a highly lethal syndrome
with mortality rates approaching 100%. Pneumonic plague progression is biphasic, with an …

Various Gram-negative bacteria possess a specialized membrane-bound protein secretion
system known as the Type III secretion system (T3SS), which transports the bacterial effector …