Alternative splicing (AS) is a key transcriptional regulation pathway. Recent studies have
shown that AS events are associated with the occurrence of complex diseases. Various …

Identifying genes associated with autism spectrum disorder (ASD) is crucial for
understanding the underlying mechanisms of the disorder. However, ASD is a complex …

Alternative splicing (AS) disruption has been linked to disorders of muscle development, as
well as muscular atrophy. However, the precise changes in AS patterns that occur during …

The present review aims to provide a short update of our understanding of the inhibitory
interneurons of the cerebellum. While these cells constitute but a minority of all cerebellar …

RNA splicing shapes the gene regulatory programs that underlie various physiological and
disease processes. Here, we present the SCASL (single-cell clustering based on alternative …

单细胞测序是一种基于单个细胞层面上获取自身细胞全部遗传信息的高通量测序技术,
揭示了单个细胞的细胞内动力学, 并通过数百万个细胞的高维目录回答生物学问题 …

Protein structure prediction with neural networks is a powerful new method for linking protein
sequence, structure, and function, but structures have generally been predicted for only a …

Single-cell RNA-seq is widely used for transcriptome profiling, but most analyses have
focused on gene-level events, with much less attention devoted to alternative splicing. Here …