Regulation of prostate cancer progression by the tumor microenvironment

SL Shiao, GCY Chu, LWK Chung - Cancer letters, 2016 - Elsevier
Prostate cancer remains the most frequently diagnosed cancer in men in North America, and
despite recent advances in treatment patients with metastatic disease continue to have poor …

Inflammation as a driver of prostate cancer metastasis and therapeutic resistance

M Archer, N Dogra, N Kyprianou - Cancers, 2020 - mdpi.com
Simple Summary Prostate cancer is the most common malignancy in men, with a high
mortality rate when disease progresses to metastasis and therapeutic resistance. Evidence …

A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer

AW Chung, K Anand, AC Anselme, AA Chan… - Science translational …, 2021 - science.org
The inducible nitric oxide signaling (iNOS) pathway is associated with poor prognosis in
triple-negative breast cancer (TNBC). Prior studies using in vivo models showed that …

Mechanisms of resistance to systemic therapy in metastatic castration-resistant prostate cancer

G Galletti, BI Leach, L Lam, ST Tagawa - Cancer treatment reviews, 2017 - Elsevier
Patients with metastatic castration-resistant prostate cancer (mCPRC) now have an
unprecedented number of approved treatment options, including chemotherapies …

The present and future of biomarkers in prostate cancer: proteomics, genomics, and immunology advancements: supplementary issue: biomarkers and their essential …

PO Gaudreau, J Stagg, D Soulières… - Biomarkers in …, 2016 - journals.sagepub.com
Prostate cancer (PC) is the second most common form of cancer in men worldwide.
Biomarkers have emerged as essential tools for treatment and assessment since the …

Expression of indoleamine 2, 3-dioxygenase induced by IFN-γ and TNF-α as potential biomarker of prostate cancer progression

I Banzola, C Mengus, S Wyler, T Hudolin… - Frontiers in …, 2018 - frontiersin.org
Inflammation has been suggested to play an important role in onset and progression of
prostate cancer (PCa). Histological analysis of prostatectomy specimens has revealed focal …

[HTML][HTML] The evolution of chemotherapy for the treatment of prostate cancer

DI Quinn, HM Sandler, LG Horvath, A Goldkorn… - Annals of …, 2017 - Elsevier
Chemotherapy has been explored as a treatment option for metastatic prostate cancer since
the early 1980s. Docetaxel, a taxane chemotherapeutic, was approved for the treatment of …

[HTML][HTML] The mechanism of the cytotoxic effect of Panax notoginseng extracts on prostate cancer cells

B Hawthorne, K Lund, S Freggiaro, R Kaga… - Biomedicine & …, 2022 - Elsevier
Abstract Introduction Panax notoginseng (Burkill) FH commonly referred to as Sanqi, is a
Chinese herb that has long been used to treat various conditions including blood disorders …

Cellular determinants and microenvironmental regulation of prostate cancer metastasis

K Rycaj, H Li, J Zhou, X Chen, DG Tang - Seminars in cancer biology, 2017 - Elsevier
Metastasis causes more than 90% of cancer-related deaths and most prostate cancer (PCa)
patients also die from metastasis. The 'metastatic cascade'is a complex biological process …

Brazilian green propolis: a novel tool to improve the cytotoxic and immunomodulatory action of docetaxel on MCF‐7 breast cancer cells and on women monocyte

E de Oliveira Cardoso, KB Santiago… - Phytotherapy …, 2022 - Wiley Online Library
Docetaxel (DTX) is used against breast cancer despite its side effects such as toxicity and
immunosuppression. Here we investigated the cytotoxic and immunomodulatory effects of …