Recent advances in droplet‐based microfluidics in liquid biopsy for cancer diagnosis
Liquid biopsy, a noninvasive technique to obtain tumor information from body fluids, is an
emerging technology for cancer diagnosis, prognosis, and monitoring, providing crucial …
emerging technology for cancer diagnosis, prognosis, and monitoring, providing crucial …
[HTML][HTML] Circulating tumor cell subpopulations predict treatment outcome in Pancreatic ductal adenocarcinoma (PDAC) patients
There is a high clinical unmet need to improve outcomes for pancreatic ductal
adenocarcinoma (PDAC) patients, either with the discovery of new therapies or biomarkers …
adenocarcinoma (PDAC) patients, either with the discovery of new therapies or biomarkers …
[HTML][HTML] A comprehensive review of the potential role of liquid biopsy as a diagnostic, prognostic, and predictive biomarker in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma is one of the most lethal malignant diseases, with a
mortality rate being close to incidence. Due to its heterogeneity and plasticity, as well as the …
mortality rate being close to incidence. Due to its heterogeneity and plasticity, as well as the …
Disseminated tumour cells in bone marrow are the source of cancer relapse after therapy
B Sai, J Xiang - Journal of cellular and molecular medicine, 2018 - Wiley Online Library
Accumulating evidence indicates that cancer cells spread much earlier than was previously
believed. Recent technological advances have greatly improved the detection methods of …
believed. Recent technological advances have greatly improved the detection methods of …
Circulating tumor cells are an independent predictor of shorter survival in patients undergoing resection for pancreatic and periampullary adenocarcinoma
H Hugenschmidt, KJ Labori, C Brunborg… - Annals of …, 2020 - journals.lww.com
Objective: We evaluated the prognostic impact of circulating tumor cells (CTCs) for patients
with presumed resectable pancreatic and periampullary cancers. Summary of Background …
with presumed resectable pancreatic and periampullary cancers. Summary of Background …
Liquid biopsies in pancreatic cancer
Introduction: Pancreatic ductal adenocarcinoma (PDAC) is a disease of high lethality.
Invasive tissue biopsies of primary or metastatic lesions remain the gold standard for …
Invasive tissue biopsies of primary or metastatic lesions remain the gold standard for …
[HTML][HTML] Propagated Circulating Tumor Cells Uncover the Potential Role of NFκB, EMT, and TGFβ Signaling Pathways and COP1 in Metastasis
Simple Summary Metastasis is the primary cause of cancer-related deaths, but is poorly
understood. Circulating tumor cells (CTCs) seed distant sites are a promising model system …
understood. Circulating tumor cells (CTCs) seed distant sites are a promising model system …
[HTML][HTML] Favorable tumor biology in locally advanced pancreatic cancer—beyond CA19-9
B Kinny-Köster, JR Habib, CL Wolfgang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Patients with pancreatic ductal adenocarcinoma (PDAC) are frequently staged as
unresectable locally advanced pancreatic cancer (LAPC) at the time of diagnosis. Recently …
unresectable locally advanced pancreatic cancer (LAPC) at the time of diagnosis. Recently …
[HTML][HTML] Epigenetics in pancreatic ductal adenocarcinoma: impact on biology and utilization in diagnostics and treatment
Simple Summary Epigenetic alterations contribute to the distinct biology of pancreatic ductal
adenocarcinoma (PDAC) and thus allow a better understanding of molecular mechanisms …
adenocarcinoma (PDAC) and thus allow a better understanding of molecular mechanisms …
[HTML][HTML] Adjuvant treatment in pancreatic cancer: shaping the future of the curative setting
A Pappalardo, EF Giunta, G Tirino, L Pompella… - Frontiers in …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease even in the early stages,
despite progresses in surgical and pharmacological treatment in recent years. High potential …
despite progresses in surgical and pharmacological treatment in recent years. High potential …