Epithelial to mesenchymal transition as mechanism of progression of pancreatic cancer: from mice to men
L Greco, F Rubbino, L Laghi - Cancers, 2022 - mdpi.com
Simple Summary The progression of pancreatic cancer (PDAC) involves a series of events
transforming the phenotype of cancer cells, namely epithelial-to-mesenchymal transition …
transforming the phenotype of cancer cells, namely epithelial-to-mesenchymal transition …
Circulating Epithelial Cells in Patients with Intraductal Papillary Mucinous Neoplasm of the Pancreas
J Kuvendjiska, F Müller, P Bronsert, S Timme-Bronsert… - Life, 2023 - mdpi.com
Intraductal papillary mucinous neoplasm (IPMN) is the most common pancreatic cyst and a
precursor of pancreatic cancer (PDAC). Since PDAC has a devastatingly high mortality rate …
precursor of pancreatic cancer (PDAC). Since PDAC has a devastatingly high mortality rate …
[HTML][HTML] Glycoprotein biomarkers for the detection of pancreatic ductal adenocarcinoma
E Llop, PE Guerrero, A Duran, S Barrabés… - World Journal of …, 2018 - ncbi.nlm.nih.gov
Pancreatic cancer (PaC) shows a clear tendency to increase in the next years and therefore
represents an important health and social challenge. Currently, there is an important need to …
represents an important health and social challenge. Currently, there is an important need to …
Next-generation sequencing in pancreatic cancer
GQ Shen, EM Aleassa, RM Walsh, G Morris-Stiff - Pancreas, 2019 - journals.lww.com
Pancreatic ductal adenocarcinoma (PDAC) is lethal, and the majority of patients present with
locally advanced or metastatic disease that is not amenable to cure. Thus, with surgical …
locally advanced or metastatic disease that is not amenable to cure. Thus, with surgical …
[HTML][HTML] Pancreatic cancer: disease dynamics, tumor biology and the role of the microenvironment
D Ansari, H Friess, M Bauden, J Samnegård… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Pancreatic cancer is known for its propensity to metastasize. Recent studies have
challenged the commonly held belief that pancreatic cancer is a stepwise process, where …
challenged the commonly held belief that pancreatic cancer is a stepwise process, where …
[HTML][HTML] Development and clinical validation of discriminatory multitarget digital droplet PCR assays for the detection of hot spot KRAS and NRAS mutations in cell-free …
S Hussung, M Follo, RFU Klar, S Michalczyk… - The Journal of Molecular …, 2020 - Elsevier
Detection and quantification of tumor-derived KRAS and NRAS mutations in plasma cell-free
DNA (cfDNA) holds great potential for cancer diagnostics and treatment response …
DNA (cfDNA) holds great potential for cancer diagnostics and treatment response …
Measurement of portal vein blood circulating tumor cells is safe and may correlate with outcomes in resected pancreatic ductal adenocarcinoma
Background This study investigated the safety and feasibility of intraoperative portal vein
blood (PVB) collection at the time of pancreatic ductal adenocarcinoma (PDAC) resection …
blood (PVB) collection at the time of pancreatic ductal adenocarcinoma (PDAC) resection …
Pancreatic cancer circulating tumor cells: applications for personalized oncology
BJ DiPardo, P Winograd, CM Court… - Expert review of …, 2018 - Taylor & Francis
Introduction: Pancreatic cancer (PC) is a highly lethal disease, in part because of early
metastasis, late diagnosis, and limited treatment options. Circulating tumor cells (CTCs) are …
metastasis, late diagnosis, and limited treatment options. Circulating tumor cells (CTCs) are …
Multiplex Digital Polymerase Chain Reaction on a Droplet Array SlipChip for Analysis of KRAS Mutations in Pancreatic Cancer
Q Hu, F Kanwal, W Lyu, J Zhang, X Liu, K Qin… - ACS …, 2022 - ACS Publications
Pancreatic cancer is a terminal disease with high mortality and very poor prognosis. A
sensitive and quantitative analysis of KRAS mutations in pancreatic cancer provides a tool …
sensitive and quantitative analysis of KRAS mutations in pancreatic cancer provides a tool …
Circulating tumour cells in pancreatic cancer: A systematic review and meta-analysis of clinicopathological implications
Background The detection and quantification of circulating tumour cells (CTCs) in pancreatic
cancer (PC) has the potential to provide prognostic information. The aim of this review was …
cancer (PC) has the potential to provide prognostic information. The aim of this review was …