[HTML][HTML] The discordance of gene mutations between circulating tumor cells and primary/metastatic tumor

Q Wang, L Zhao, L Han, X Tuo, S Ma, Y Wang… - Molecular Therapy …, 2019 - cell.com
Circulating tumor cells (CTCs) are an important part in the field of" liquid biopsy." However,
major questions remain to be answered whether the mutations in the CTCs represent the …

[HTML][HTML] Predictive biomarkers for a personalized approach in resectable pancreatic cancer

V Merz, D Mangiameli, C Zecchetto, A Quinzii… - Frontiers in …, 2022 - frontiersin.org
The mainstay treatment for patients with immediate resectable pancreatic cancer remains
upfront surgery, which represents the only potentially curative strategy. Nevertheless, the …

[HTML][HTML] Cancer-associated Macrophage-like Cells in Patients with Non-metastatic Adenocarcinoma of the Esophagus-Cytomorphological Heterogeneity

C Braun, C Schmoor, S Timme-Bronsert… - Journal of …, 2023 - ncbi.nlm.nih.gov
Introduction: Esophageal adenocarcinoma (EAC) often recurs systemically despite therapy
with a curative aim. New diagnostic and therapeutic approaches are urgently needed. A …

Circulating tumour cell isolation, analysis and clinical application

XL Zhang, PP Xie, KT Zhang, W Zhang - Cellular Oncology, 2023 - Springer
Abstract Background Circulating tumour cells (CTCs) are cancer cells that circulate in the
bloodstream after being shed from solid tumours. They can lead to tumour recurrence and …

[HTML][HTML] Single-cell omics: a new perspective for early detection of pancreatic cancer?

Q Wang, B Šabanović, A Awada, C Reina… - European Journal of …, 2023 - Elsevier
Pancreatic cancer is one of the most lethal cancers, mostly due to late diagnosis and limited
treatment options. Early detection of pancreatic cancer in high-risk populations bears the …

Critical role of KRAS mutation in pancreatic ductal adenocarcinoma

Z Fan, K Fan, C Yang, Q Huang, Y Gong… - Translational Cancer …, 2018 - tcr.amegroups.org
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human cancers
worldwide. Little progress has been made in recent years concerning its diagnosis and …

[HTML][HTML] Label-free enrichment of rare unconventional circulating neoplastic cells using a microfluidic dielectrophoretic sorting device

J Montoya Mira, AA Sapre, BS Walker… - Communications …, 2021 - nature.com
Cellular circulating biomarkers from the primary tumor such as circulating tumor cells (CTCs)
and circulating hybrid cells (CHCs) have been described to harbor tumor-like phenotype …

[HTML][HTML] Phenotypic characteristics of circulating tumor cells and predictive impact for efficacy of chemotherapy in patients with pancreatic cancer: a prospective study

HS Lee, EH Jung, H Shin, CS Park, SB Park… - Frontiers in …, 2023 - frontiersin.org
Objective Early chemoresistance and tumor mass progression are associated with poor
prognosis in pancreatic ductal adenocarcinoma (PDAC). Circulating tumor cells (CTCs) …

[HTML][HTML] Mesenchymal characteristics and predictive biomarkers on circulating tumor cells for therapeutic strategy

T Okabe, S Togo, Y Fujimoto, J Watanabe, I Sumiyoshi… - Cancers, 2020 - mdpi.com
Simple Summary Circulating tumor cells (CTCs) are the seeds that spread through the
circulatory system and generate the metastatic sites. Among the various phenotypes …

[HTML][HTML] The value of circulating tumor cells in the prognosis and treatment of pancreatic cancer

K Luo, X Wang, X Zhang, Z Liu, S Huang, R Li - Frontiers in Oncology, 2022 - frontiersin.org
In the past few decades, tumor diagnosis and treatment theory have developed in a variety
of directions. The number of people dying from pancreatic cancer increases while the …