Optimisation of an electrochemical DNA sensor for measuring KRAS G12D and G13D point mutations in different tumour types
B Attoye, MJ Baker, F Thomson, C Pou, DK Corrigan - Biosensors, 2021 - mdpi.com
Circulating tumour DNA (ctDNA) is widely used in liquid biopsies due to having a presence
in the blood that is typically in proportion to the stage of the cancer and because it may …
in the blood that is typically in proportion to the stage of the cancer and because it may …
Droplet digital PCR assay provides intrahepatic HBV cccDNA quantification tool for clinical application
S Hayashi, M Isogawa, K Kawashima, K Ito… - Scientific Reports, 2022 - nature.com
The persistence of covalently closed circular DNA (cccDNA) poses a major obstacle to
curing chronic hepatitis B (CHB). Here, we used droplet digital PCR (ddPCR) for cccDNA …
curing chronic hepatitis B (CHB). Here, we used droplet digital PCR (ddPCR) for cccDNA …
Non-metastatic esophageal adenocarcinoma: Circulating tumor cells in the course of multimodal tumor treatment
J Kuvendjiska, P Bronsert, V Martini, S Lang… - Cancers, 2019 - mdpi.com
Background: Isolation of circulating tumor cells (CTC) holds the promise to improve
response-prediction and personalization of cancer treatment. In this study, we test a filtration …
response-prediction and personalization of cancer treatment. In this study, we test a filtration …
[HTML][HTML] Clinical implications and perspectives of portal venous circulating tumor cells in pancreatic cancer
SW Ko, SB Yoon - World Journal of Gastrointestinal Oncology, 2023 - ncbi.nlm.nih.gov
Despite recent improvements in the diagnosis and treatment of pancreatic cancer (PC),
clinical outcomes remain dismal. Moreover, there are no effective prognostic or predictive …
clinical outcomes remain dismal. Moreover, there are no effective prognostic or predictive …
High-throughput manipulation of circulating tumor cells using a multiple single-cell encapsulation system with a digital micromirror device
R Negishi, K Takai, T Tanaka, T Matsunaga… - Analytical …, 2018 - ACS Publications
Circulating tumor cells (CTCs) are potential precursors of metastatic cancer, and genomic
information obtained from CTCs have the potential to provide new insights into the biology of …
information obtained from CTCs have the potential to provide new insights into the biology of …
Limited clinical and diagnostic utility of circulating tumor DNA detection in patients with early-stage well-differentiated thyroid cancer: comparison with benign thyroid …
YJ Suh, MJ Kwon, HM Noh, HK Lee, YJ Ra, NY Kim - Healthcare, 2021 - mdpi.com
Limited data are available on the diagnostic utility of circulating tumor DNA (ctDNA) in early-
stage thyroid cancers for BRAF, KRAS, NRAS, and TERT promoter mutations, which are …
stage thyroid cancers for BRAF, KRAS, NRAS, and TERT promoter mutations, which are …
Genetic Signature of Human Pancreatic Cancer and Personalized Targeting
SJ Reshkin, RA Cardone, T Koltai - Cells, 2024 - mdpi.com
Pancreatic cancer is a highly lethal disease with a 5-year survival rate of around 11–12%.
Surgery, being the treatment of choice, is only possible in 20% of symptomatic patients. The …
Surgery, being the treatment of choice, is only possible in 20% of symptomatic patients. The …
[HTML][HTML] Stem cell-like circulating tumor cells identified by Pep@ MNP and their clinical significance in pancreatic cancer metastasis
X Chu, X Zhong, S Zang, M Wang, P Li, Y Ma… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Objective The circulating tumor cells (CTCs) could be captured by the peptide functionalized
magnetic nanoparticles (Pep@ MNP) detection system in pancreatic ductal adenocarcinoma …
magnetic nanoparticles (Pep@ MNP) detection system in pancreatic ductal adenocarcinoma …
Circulating tumor cells: metastases caught in the act
S Zheng, MD Girgis, JS Tomlinson - Annals of Surgery, 2023 - journals.lww.com
Pancreatic cancer (PC) is a relatively lethal disease, characterized by early metastasis, late
diagnosis, and limited effective treatment options. Understaging at diagnosis is frequent and …
diagnosis, and limited effective treatment options. Understaging at diagnosis is frequent and …
Research progress on the multi-omics and survival status of circulating tumor cells
Q Xie, S Liu, S Zhang, L Liao, Z Xiao, S Wang… - Clinical and …, 2024 - Springer
In the dynamic process of metastasis, circulating tumor cells (CTCs) emanate from the
primary solid tumor and subsequently acquire the capacity to disengage from the basement …
primary solid tumor and subsequently acquire the capacity to disengage from the basement …