Circulating tumour DNA (ctDNA) is widely used in liquid biopsies due to having a presence
in the blood that is typically in proportion to the stage of the cancer and because it may …

The persistence of covalently closed circular DNA (cccDNA) poses a major obstacle to
curing chronic hepatitis B (CHB). Here, we used droplet digital PCR (ddPCR) for cccDNA …

Background: Isolation of circulating tumor cells (CTC) holds the promise to improve
response-prediction and personalization of cancer treatment. In this study, we test a filtration …

Despite recent improvements in the diagnosis and treatment of pancreatic cancer (PC),
clinical outcomes remain dismal. Moreover, there are no effective prognostic or predictive …

Circulating tumor cells (CTCs) are potential precursors of metastatic cancer, and genomic
information obtained from CTCs have the potential to provide new insights into the biology of …

Limited data are available on the diagnostic utility of circulating tumor DNA (ctDNA) in early-
stage thyroid cancers for BRAF, KRAS, NRAS, and TERT promoter mutations, which are …

Pancreatic cancer is a highly lethal disease with a 5-year survival rate of around 11–12%.
Surgery, being the treatment of choice, is only possible in 20% of symptomatic patients. The …

Objective The circulating tumor cells (CTCs) could be captured by the peptide functionalized
magnetic nanoparticles (Pep@ MNP) detection system in pancreatic ductal adenocarcinoma …

Pancreatic cancer (PC) is a relatively lethal disease, characterized by early metastasis, late
diagnosis, and limited effective treatment options. Understaging at diagnosis is frequent and …

In the dynamic process of metastasis, circulating tumor cells (CTCs) emanate from the
primary solid tumor and subsequently acquire the capacity to disengage from the basement …