The neocortex is a complex neurobiological system with many interacting regions. How
these regions work together to subserve flexible behavior and cognition has become …

The anatomy of the brain necessarily constrains its function, but precisely how remains
unclear. The classical and dominant paradigm in neuroscience is that neuronal dynamics …

Traditionally, in neuroimaging, model-free analyses are used to find significant differences
between brain states via signal detection theory. Depending on the a priori assumptions …

Model-based data analysis of whole-brain dynamics links the observed data to model
parameters in a network of neural masses. Recently, studies focused on the role of regional …

How does the organization of neural information processing enable humans' sophisticated
cognition? Here we decompose functional interactions between brain regions into …

Network control theory is increasingly used to profile the brain's energy landscape via
simulations of neural dynamics. This approach estimates the control energy required to …

How is the information-processing architecture of the human brain organised, and how does
its organisation support consciousness? Here, we combine network science and a rigorous …

This study examines the impact of sample size on predicting cognitive and mental health
phenotypes from brain imaging via machine learning. Our analysis shows a 3-to 9-fold …

Psychedelics including lysergic acid diethylamide (LSD) and psilocybin temporarily alter
subjective experience through their neurochemical effects. Serotonin 2a (5-HT2a) receptor …

Cortical variations in cytoarchitecture form a sensory-fugal axis that shapes regional profiles
of extrinsic connectivity and is thought to guide signal propagation and integration across …